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Hard X-ray index of refraction tomography of a whole rabbit knee joint: A feasibility study

Authors :
Annie Horng
Alberto Mittone
Tobias Geith
Paola Coan
Tilo Baumbach
Alberto Bravin
S. Gasilov
Gasilov, S
Mittone, A
Horng, A
Geith, T
Bravin, A
Baumbach, T
Coan, P
Source :
Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB). 32(12)
Publication Year :
2016

Abstract

We report results of the computed tomography reconstruction of the index of refraction in a whole rabbit knee joint examined at the photon energy of 51 keV. Refraction based images make it possible to delineate the bone, cartilage, and soft tissues without adjusting the contrast window width and level. Density variations, which are related to tissue composition and are not visible in absorption X-ray images, are detected in the obtained refraction based images. We discuss why refraction-based images provide better detectability of low contrast features than absorption images.

Details

ISSN :
1724191X
Volume :
32
Issue :
12
Database :
OpenAIRE
Journal :
Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)
Accession number :
edsair.doi.dedup.....f02d84746d49291ce5ef8fed7841d97b