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The Relationship of the Post-reflux Swallow-induced Peristaltic Wave Index and Esophageal Baseline Impedance with Gastroesophageal Reflux Disease Symptoms
- Source :
- Journal of Neurogastroenterology and Motility
- Publication Year :
- 2017
- Publisher :
- Korean Society of Neurogastroenterology and Motility, 2017.
-
Abstract
- Background/Aims The post-reflux swallow-induced peristaltic wave (PSPW) index and esophageal baseline impedance (BI) are novel impedance parameters used to evaluate esophageal chemical clearance and mucosal integrity. However, their relationship with reflux symptoms is not known. We aim to evaluate the correlations of PSPW index and esophageal BI with gastroesophageal reflux disease (GERD) symptoms. Methods We performed a retrospective review of multichannel intraluminal impedance and pH (MII-pH) tracings in patients with suspected GERD. Reflux symptoms were also analyzed from checklists using ordinal scales. The PSPW index and esophageal BIs in 6 spots (z1-z6) were measured. Bivariate (Spearman) correlation was used to analyze the relationship between the PSPW index or esophageal BI, and the degree of GERD symptoms measured. Results The MII-pH records of 143 patients were analyzed. The PSPW index was significantly lower in patients who had heartburn and negatively correlated with the degree of heartburn (r = -0.186, P < 0.05). On the contrary, the PSPW index was not significantly correlated with the degree of dysphagia (r = -0.013, P = 0.874). Distal esophageal BI was not significantly correlated with heartburn, but negatively correlated with the degree of dysphagia (z3: r = -0.328, z4: r = -0.361, z5: r = -0.316, z6: r = -0.273; P < 0.05). Conclusions These findings suggest that delayed chemical clearance of the esophagus may induce heartburn, but that it is not related to dysphagia. However, a lack of esophageal mucosal integrity may be related to dysphagia.
- Subjects :
- medicine.medical_specialty
Disease
Gastroenterology
03 medical and health sciences
0302 clinical medicine
Heartburn
PSPW index
Internal medicine
Esophageal baseline impedance
medicine
otorhinolaryngologic diseases
Baseline impedance
Esophagus
Peristalsis
business.industry
Reflux
Dysphagia
medicine.disease
digestive system diseases
medicine.anatomical_structure
Gastroesophageal reflux
030220 oncology & carcinogenesis
GERD
030211 gastroenterology & hepatology
Original Article
Neurology (clinical)
medicine.symptom
business
Subjects
Details
- Language :
- English
- ISSN :
- 20930887 and 20930879
- Volume :
- 23
- Issue :
- 2
- Database :
- OpenAIRE
- Journal :
- Journal of Neurogastroenterology and Motility
- Accession number :
- edsair.doi.dedup.....f0cc1502f287df6a42c1cb9a49eecda5