Back to Search
Start Over
Experimental model of atelectasis in newborn piglets
- Source :
- Respiratory care. 59(1)
- Publication Year :
- 2013
-
Abstract
- BACKGROUND: There are few studies using animal models in chest physical therapy. However, there are no models to assess these effects in newborns. This study aimed to develop a model of obstructive atelectasis induced by artificial mucus injection in the lungs of newborn piglets, for the study of neonatal physiotherapy. METHODS: Thirteen newborn piglets received artificial mucus injection via the endotracheal tube. X-rays and blood gas analysis confirmed the atelectasis. RESULTS: The model showed consistent results between oxygenation parameters and radiological findings. Ten (76.9%) of the 13 piglets responded to the intervention. This did not significantly differ from the expected percentage of 50% by the binomial test (95% CI 46.2–95%, P = .09). CONCLUSIONS: Our model of atelectasis in newborn piglets is both feasible and appropriate to evaluate the impact of physical therapies on atelectasis in newborns.
- Subjects :
- Pulmonary and Respiratory Medicine
Pulmonary Atelectasis
Swine
medicine.medical_treatment
Atelectasis
Critical Care and Intensive Care Medicine
Chest Physical Therapy
fluids and secretions
Medicine
Animals
Physical Therapy Modalities
Endotracheal tube
Blood gas analysis
Mechanical ventilation
business.industry
Experimental model
General Medicine
Oxygenation
medicine.disease
Mucus
Oxygen
Radiography
Disease Models, Animal
Animals, Newborn
Anesthesia
business
Subjects
Details
- ISSN :
- 19433654
- Volume :
- 59
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- Respiratory care
- Accession number :
- edsair.doi.dedup.....f10d85f510a8b301b13fcb542eda1ec8