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Sleep Duration Patterns in Early to Middle Adulthood and Subsequent Risk of Type 2 Diabetes in Women
- Source :
- Diabetes Care
- Publication Year :
- 2020
- Publisher :
- American Diabetes Association, 2020.
-
Abstract
- OBJECTIVE To identify sleep duration trajectories from early to middle adulthood and their associations with incident type 2 diabetes. RESEARCH DESIGN AND METHODS Using a group-based modeling approach, we identified sleep duration trajectories based on sleep duration in ages 20–25, 26–35, 36–45, and 46+ years, which were retrospectively assessed in 2009 among 60,068 women from the Nurses’ Health Study II (median age 54.9 years) who were free of diabetes, cardiovascular disease, and cancer. We investigated the prospective associations between sleep duration trajectories and diabetes risk (2009–2017) using multivariable Cox proportional hazards models. RESULTS We documented 1,797 incident diabetes cases over a median follow-up of 7.8 years (442,437 person-years). Six sleep duration trajectories were identified: persistent 5-, 6-, 7-, or 8-h sleep duration and increased or decreased sleep duration. After multivariable adjustment for diabetes risk factors, compared with the persistent 7-h sleep duration group, the hazard ratio was 1.43 (95% CI 1.10, 1.84) for the 5-h group, 1.17 (1.04, 1.33) for the 6-h group, 0.96 (0.84, 1.10) for the 8-h group, 1.33 (1.09, 1.61) for the increased sleep duration group, and 1.32 (1.10, 1.59) for the decreased sleep duration group. Additional adjustment for time-updated comorbidities and BMI attenuated these associations, although a significantly higher risk remained in the decreased sleep duration group (1.24 [1.03, 1.50]). CONCLUSIONS Persistent short sleep duration or changes in sleep duration from early to middle adulthood were associated with higher risk of type 2 diabetes in later life. These associations were weaker after obesity and metabolic comorbidities were accounted for.
- Subjects :
- Adult
Research design
Pediatrics
medicine.medical_specialty
Time Factors
Diabetes risk
Endocrinology, Diabetes and Metabolism
030209 endocrinology & metabolism
Comorbidity
Disease
Type 2 diabetes
03 medical and health sciences
0302 clinical medicine
Risk Factors
Diabetes mellitus
Internal Medicine
medicine
Humans
Prospective Studies
030212 general & internal medicine
Epidemiology/Health Services Research
Retrospective Studies
Advanced and Specialized Nursing
business.industry
Proportional hazards model
Hazard ratio
Age Factors
Middle Aged
medicine.disease
Obesity
Diabetes Mellitus, Type 2
Female
Sleep
business
Subjects
Details
- ISSN :
- 19355548 and 01495992
- Volume :
- 43
- Database :
- OpenAIRE
- Journal :
- Diabetes Care
- Accession number :
- edsair.doi.dedup.....f1122f95513785bc10f0d1daa094cd54