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Genomic characterization of an extensively drug-resistant KPC-2-producing Klebsiella pneumoniae ST855 (CC258) only susceptible to ceftazidime-avibactam isolated in Brazil
- Source :
- Diagnostic Microbiology and Infectious Disease. 89:324-327
- Publication Year :
- 2017
- Publisher :
- Elsevier BV, 2017.
-
Abstract
- In this study, we describe the genetic features of an XDR KPC-2-producing Klebsiella pneumoniae isolate by using whole-genome sequencing, its clinical-epidemiological context and susceptibility against antimicrobial combinations. The isolate belongs to clonal complex 258 and harbors several acquired genes and mutations associated with antimicrobial resistance.
- Subjects :
- 0301 basic medicine
Microbiology (medical)
Klebsiella pneumoniae
030106 microbiology
Ceftazidime
Context (language use)
Microbial Sensitivity Tests
Drug resistance
Microbiology
03 medical and health sciences
Antibiotic resistance
Plasmid
Bacterial Proteins
Drug Resistance, Multiple, Bacterial
medicine
biology
Sequence Analysis, DNA
General Medicine
Chromosomes, Bacterial
Ceftazidime/avibactam
Antimicrobial
biology.organism_classification
Anti-Bacterial Agents
Drug Combinations
030104 developmental biology
Infectious Diseases
Azabicyclo Compounds
Brazil
Plasmids
medicine.drug
Subjects
Details
- ISSN :
- 07328893
- Volume :
- 89
- Database :
- OpenAIRE
- Journal :
- Diagnostic Microbiology and Infectious Disease
- Accession number :
- edsair.doi.dedup.....f11978b45e366191d3ea1e9c60e3cbf6