Back to Search
Start Over
Evaluation of power of the Illumina HumanOmni5M-4v1 BeadChip to detect risk variants for human complex diseases
- Source :
- European Journal of Human Genetics. 24:1029-1034
- Publication Year :
- 2015
- Publisher :
- Springer Science and Business Media LLC, 2015.
-
Abstract
- Although emerging sequencing technologies can characterize all genetic variants, the cost is still high. Illumina released the HumanOmni5M-4v1 (Omni5) genotype array with ~4.3M assayed SNPs, a much denser array compared with other available arrays. The Omni5 balances both cost and array density. In this article, we illustrate the power of Omni5 to detect genetic associations. The Omni5 includes variants with a wide range of minor allele frequencies down to
- Subjects :
- 0301 basic medicine
Genotyping Techniques
Quantitative Trait Loci
Single-nucleotide polymorphism
Genome-wide association study
Computational biology
Quantitative trait locus
Biology
Hippocampus
Sensitivity and Specificity
Article
03 medical and health sciences
Bone Density
Genetics
Humans
Genetic Testing
International HapMap Project
1000 Genomes Project
Genotyping
Genetics (clinical)
Oligonucleotide Array Sequence Analysis
Organ Size
Minor allele frequency
030104 developmental biology
Mutation
Imputation (genetics)
Genome-Wide Association Study
Subjects
Details
- ISSN :
- 14765438 and 10184813
- Volume :
- 24
- Database :
- OpenAIRE
- Journal :
- European Journal of Human Genetics
- Accession number :
- edsair.doi.dedup.....f13224110fff672ee376538c508f9f1c