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Assessing Alzheimer's disease patients' quality of life: Discrepancies between patient and caregiver perspectives
- Source :
- Alzheimer's & Dementia. 12:427-437
- Publication Year :
- 2015
- Publisher :
- Wiley, 2015.
-
Abstract
- Introduction Quality of life (QOL) is an important dimension to consider in Alzheimer's disease (AD), but few large-scale studies have analyzed self and caregiver reports of patient QOL. Methods Patient QOL was evaluated in a cohort of 574 AD patients with the QOL-AD scale over 2 years. Results Caregiver reports of patient QOL were lower at baseline than self reports. Older patient age was associated with overestimation of QOL by caregivers, whereas neuropsychiatric inventory score and caregiver burden were associated with underestimation. Activities of daily living limitation, depressive symptoms, and caregiver burden were systematically associated with poorer QOL, whereas caregiver relationship and apathy were associated with poorer QOL only for self reports or caregiver reports, respectively. Cognitive function and professional care were not associated with QOL. Self-rated patient QOL did not change over time, whereas disease severity markers and caregiver-rated patient QOL declined. Discussion It is important to assess both self and caregiver ratings when assessing patient QOL.
- Subjects :
- Male
Gerontology
Aging
Time Factors
Activities of daily living
Epidemiology
Disease
Severity of Illness Index
03 medical and health sciences
Cellular and Molecular Neuroscience
0302 clinical medicine
Cost of Illness
Developmental Neuroscience
Quality of life
Alzheimer Disease
Humans
Medicine
Apathy
Longitudinal Studies
Aged
Aged, 80 and over
Psychological Tests
030214 geriatrics
business.industry
Health Policy
Age Factors
Cognition
Caregiver burden
Neuropsychiatric inventory
humanities
Psychiatry and Mental health
Caregivers
Cohort
Disease Progression
Quality of Life
Female
Self Report
Neurology (clinical)
Geriatrics and Gerontology
medicine.symptom
business
030217 neurology & neurosurgery
Follow-Up Studies
Clinical psychology
Subjects
Details
- ISSN :
- 15525279 and 15525260
- Volume :
- 12
- Database :
- OpenAIRE
- Journal :
- Alzheimer's & Dementia
- Accession number :
- edsair.doi.dedup.....f1333b4bd4d5254fbd6aafa048118db9