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Aberrant Awake Spontaneous Brain Activity in Obstructive Sleep Apnea: A Review Focused on Resting-State EEG and Resting-State fMRI
- Source :
- Frontiers in Neurology, Frontiers in Neurology, Vol 11 (2020)
- Publication Year :
- 2020
-
Abstract
- As one of the most common sleep-related respiratory disorders, obstructive sleep apnea (OSA) is characterized by excessive snoring, repetitive apnea, arousal, sleep fragmentation, and intermittent nocturnal hypoxemia. Focused on the resting-state brain imaging techniques, we reviewed the OSA-related resting-state electroencephalogram and resting-state functional magnetic resonance imaging (rsfMRI) studies. Compared with the healthy control group, patients with OSA presented increased frontal and central δ/θ powers during resting-state wakefulness, and their slow-wave activity showed a positive correlation with apnea–hypopnea index. For rsfMRI, the prefrontal cortex and insula may be the vital regions for OSA and are strongly related to the severity of the disease. Meanwhile, some large-scale brain networks, such as the default-mode network, salience network, and central executive network, play pivotal roles in the pathology of OSA. We then discussed the contribution of resting-state brain imaging as an evaluation approach for disease interventions. Finally, we briefly introduced the effects of OSA-related physiological and mental diseases and discussed some future research directions from the perspective of resting-state brain imaging.
- Subjects :
- Brain activity and meditation
Review
Electroencephalography
lcsh:RC346-429
03 medical and health sciences
0302 clinical medicine
resting-state
brain activity
medicine
Prefrontal cortex
lcsh:Neurology. Diseases of the nervous system
obstructive sleep apnea
medicine.diagnostic_test
Resting state fMRI
business.industry
Apnea
medicine.disease
functional magnetic resonance imaging
respiratory tract diseases
Obstructive sleep apnea
030228 respiratory system
Neurology
Wakefulness
Neurology (clinical)
medicine.symptom
Functional magnetic resonance imaging
business
Neuroscience
030217 neurology & neurosurgery
electroencephalography
Subjects
Details
- ISSN :
- 16642295
- Volume :
- 11
- Database :
- OpenAIRE
- Journal :
- Frontiers in neurology
- Accession number :
- edsair.doi.dedup.....f15f73038f6eecdc8c154f591f4d0014