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The impact of preoperative breast MRI on the re-excision rate in invasive lobular carcinoma of the breast
- Source :
- Breast Cancer Research and Treatment, 119(2), 415-422. Springer, Cham, Breast Cancer Research and Treatment, Breast Cancer Research and Treatment, Springer Verlag, 2009, 119 (2), pp.415-422. ⟨10.1007/s10549-009-0616-6⟩, Breast Cancer Research and Treatment, 119, 415-22, Breast Cancer Research and Treatment, 119, 2, pp. 415-22
- Publication Year :
- 2009
-
Abstract
- Contains fulltext : 87794.pdf (Publisher’s version ) (Closed access) Re-excision rates after breast conserving surgery(BCS) of invasive lobular carcinoma (ILC) are high.Preoperative breast MRI has the potential to reduce re-excision rates, but may lead to an increased rate of mastectomies. Hence, we assessed the influence of preoperative breast MRI on the re-excision rate and the rate of mastectomies. We performed a retrospective cohort study of a consecutive series of patients with ILC who presented in one of two dedicated tertiary cancer centers between 1993 and 2005. We assessed the initial type of surgery(BCS or mastectomy), the re-excision rate and the final type of surgery. Patients were stratified into two groups:those who received preoperative MRI (MR? group) and those who did not (MR- group). In the MR- group, 27%of the patients underwent a re-excision after initial BCS. In the MR? group, this rate was significantly lower at 9%.The odds ratio was 3.64 (95% CI: 1.30-10.20, P = 0.010).There was a trend towards a lower final mastectomy rate in the MR? group compared to the MR- group (48 vs. 59%,P = 0.098). In conclusion, preoperative MRI in patients with ILC can reduce re-excision rates without increasing the rate of mastectomies. 01 januari 2010
- Subjects :
- Adult
Reoperation
Cancer Research
medicine.medical_specialty
Time Factors
medicine.medical_treatment
Breast Neoplasms
Aetiology, screening and detection [ONCOL 5]
Mastectomy, Segmental
Preoperative care
Risk Assessment
Breast cancer
Translational research [ONCOL 3]
Predictive Value of Tests
Breast conserving surgery
Preoperative Care
Breast-conserving surgery
Odds Ratio
Medicine
Breast MRI
Humans
Neoplasm Invasiveness
skin and connective tissue diseases
Mastectomy
Aged
Netherlands
Retrospective Studies
Aged, 80 and over
medicine.diagnostic_test
business.industry
Retrospective cohort study
Middle Aged
medicine.disease
Invasive lobular carcinoma
Magnetic Resonance Imaging
Surgery
Carcinoma, Lobular
Treatment Outcome
Oncology
Female
Breast disease
Radiology
business
Re-excision rate
Subjects
Details
- ISSN :
- 15737217 and 01676806
- Volume :
- 119
- Issue :
- 2
- Database :
- OpenAIRE
- Journal :
- Breast cancer research and treatment
- Accession number :
- edsair.doi.dedup.....f1653a21ce3d1a9b22888d987c4a9883