Gastric bypass simultaneously improves adipose tissue function and insulin-dependent type 2 diabetes mellitus

Authors :: Katharina M. Scheurlen
Markus W. Büchler
Stefan Kopf
Thomas Fleming
Barbara Israel
Adrian T. Billeter
Asa Hidmark
S Vittas
Beat P. Müller-Stich
Source :: Langenbeck's Archives of Surgery. 402:901-910
Publication Year :: 2017
Publisher :: Springer Science and Business Media LLC, 2017.
Abstract: The underlying causes of type 2 diabetes (T2DM) remain poorly understood. Adipose tissue dysfunction with high leptin, inflammation, and increased oxidative stress may play a pivotal role in T2DM development in obese patients. Little is known about the changes in the adipose tissue after Roux-Y gastric bypass (RYGB) in non-severely obese patients (BMI

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