Back to Search
Start Over
Development of a Bioactive Flowable Resin Composite Containing a Zinc-Doped Phosphate-Based Glass
- Source :
- Nanomaterials, Volume 10, Issue 11, Nanomaterials, Vol 10, Iss 2311, p 2311 (2020)
- Publication Year :
- 2020
- Publisher :
- MDPI, 2020.
-
Abstract
- Flowable resins used for dental restoration are subject to biofilm formation. Zinc has antibacterial properties. Thus, we prepared a zinc-doped phosphate-based glass (Zn-PBG) to dope a flowable resin and evaluated the antibacterial activity of the composite against Streptococcus mutans (S. mutans) to extrapolate the preventative effect toward secondary caries. The composites were prepared having 0 (control), 1.9, 3.8, and 5.4 wt.% Zn-PBG. The flexural strength, elastic modulus, microhardness, depth of cure, ion release, inhibition zone size, and number of colony-forming units were evaluated and analyzed using ANOVA. The flexural strength of the control was significantly higher than those of Zn-PBG samples (p &lt<br />0.05). However, all samples meet the International Standard, ISO 4049. The microhardness was not significantly different for the control group and 1.9 and 3.8 wt.% groups, but the 5.4 wt.% Zn-PBG group had a significantly lower microhardness (p &lt<br />0.05). Further, the composite resins increasingly released P, Ca, Na, and Zn ions with an increase in Zn-PBG content (p &lt<br />0.05). The colony-forming unit count revealed a significant reduction in S. mutans viability (p &lt<br />0.05) with increase in Zn-PBG content. Therefore, the addition of Zn-PBG to flowable composite resins enhances antibacterial activity and could aid the prevention of secondary caries.
- Subjects :
- General Chemical Engineering
medicine.medical_treatment
Composite number
chemistry.chemical_element
02 engineering and technology
Zinc
Article
biofilm
lcsh:Chemistry
03 medical and health sciences
chemistry.chemical_compound
0302 clinical medicine
Flexural strength
Flowable Composite
medicine
General Materials Science
tooth remineralization
biology
dental restoration
bioactive material
zinc
bioglass
030206 dentistry
021001 nanoscience & nanotechnology
biology.organism_classification
Phosphate
Streptococcus mutans
flowable resin composite
antibacterial
lcsh:QD1-999
chemistry
plaque prevention
0210 nano-technology
Antibacterial activity
Dental restoration
Nuclear chemistry
Subjects
Details
- Language :
- English
- ISSN :
- 20794991
- Volume :
- 10
- Issue :
- 11
- Database :
- OpenAIRE
- Journal :
- Nanomaterials
- Accession number :
- edsair.doi.dedup.....f30dbbb378674f20272b35e8a055477d