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A powerful, practical and chemoselective synthesis of 2-anilinoalkanols catalyzed by Bi(TFA)3 or Bi(OTf)3 in the presence of molten TBAB
- Source :
- Tetrahedron Letters. 45:3525-3529
- Publication Year :
- 2004
- Publisher :
- Elsevier BV, 2004.
-
Abstract
- A facile and efficient synthesis of β-amino alcohols by ring opening of epoxides with anilines in good to excellent yields in the presence of catalytic amounts of Bi(TFA) 3 or Bi(OTf) 3 via the use of molten tetrabutylammonium bromide (TBAB) as an ionic liquid is described. In addition, the observed chemoselectivity can be considered as a noteworthy advantage of this method.
Details
- ISSN :
- 00404039
- Volume :
- 45
- Database :
- OpenAIRE
- Journal :
- Tetrahedron Letters
- Accession number :
- edsair.doi.dedup.....f32366bb0ff0ff8d3276c412e0b0f473