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Evaluation of two TaqMan PCR assays for the detection of HIV-1 proviral DNA in blood samples

Authors :
Loree C. Heller
Shannon M. Moroney
Ray H. Widen
Source :
Journal of Microbiological Methods. 65:350-353
Publication Year :
2006
Publisher :
Elsevier BV, 2006.

Abstract

This study compared two published TaqMan PCR assays targeting different regions of the HIV-1 genome for detection of HIV-1 proviral DNA. The gag specific PCR demonstrated a lower sensitivity than the assay targeting the LTR region. The LTR assay is a highly reproducible and specific technique for HIV-1 proviral DNA detection.

Details

ISSN :
01677012
Volume :
65
Database :
OpenAIRE
Journal :
Journal of Microbiological Methods
Accession number :
edsair.doi.dedup.....f345ad35a059767dbe60f2e2c672ba72
Full Text :
https://doi.org/10.1016/j.mimet.2005.08.003