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The Effect of Iron Fortification on Iron (Fe) Status and Inflammation: A Randomized Controlled Trial
- Source :
- PLoS ONE, Vol 11, Iss 12, p e0167458 (2016), PLoS ONE
- Publication Year :
- 2016
- Publisher :
- Public Library of Science (PLoS), 2016.
-
Abstract
- Background Iron deficiency (ID) is common in toddlers in developing countries. Iron fortified or meat-based complementary foods may be effective to prevent ID. Objective Our objective was to compare iron status at 18 months and growth from 6 to 18 months in rural poor toddlers fed 3 different complementary foods. Methods The study was nested within a larger trial in which 6-month-old infants were randomized to receive 50g/d meat (MG), an equi-caloric fortified cereal supplement (FG) or local cereal supplement (LG) for 1 year. Hb, sTfR, HsCRP, ferritin and AGP were measured in 410 blood samples collected by a random sampling (MG, 137; FG, 140; LG, 133); calprotectin was measured in feces. Body iron = -[log (sTfR ×1000/ferritin)-2.8229] /0.1207. ID = ferritin
- Subjects :
- Male
0301 basic medicine
Pediatrics
lcsh:Medicine
Pathology and Laboratory Medicine
Systemic inflammation
Biochemistry
Gastroenterology
law.invention
Families
Randomized controlled trial
Animal Products
law
Medicine and Health Sciences
lcsh:Science
Immune Response
Children
Multidisciplinary
Anemia, Iron-Deficiency
biology
Nutritional Deficiencies
Agriculture
Anemia
Hematology
Iron deficiency
Plants
Food, Fortified
Female
Infant Food
medicine.symptom
Infants
Research Article
medicine.medical_specialty
Meat
Iron
Immunology
Crops
Research and Analysis Methods
03 medical and health sciences
Signs and Symptoms
Model Organisms
Diagnostic Medicine
Plant and Algal Models
Internal medicine
medicine
Humans
Grasses
Iron Deficiency Anemia
Developing Countries
Feces
Nutrition
Inflammation
Ferritin
Toddlers
030109 nutrition & dietetics
business.industry
lcsh:R
Organisms
Infant
Biology and Life Sciences
Proteins
Protein Complexes
medicine.disease
Diet
Cross-Sectional Studies
Iron-deficiency anemia
Food
Age Groups
Dietary Supplements
Ferritins
People and Places
Iron Deficiency
biology.protein
Population Groupings
lcsh:Q
Rice
Calprotectin
Edible Grain
business
Leukocyte L1 Antigen Complex
Crop Science
Cereal Crops
Subjects
Details
- Language :
- English
- ISSN :
- 19326203
- Volume :
- 11
- Issue :
- 12
- Database :
- OpenAIRE
- Journal :
- PLoS ONE
- Accession number :
- edsair.doi.dedup.....f349d9e4abe88cb18121b473e7468f0e