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Coronaviruses post-SARS: update on replication and pathogenesis
- Source :
- Nature Reviews Microbiology
- Publication Year :
- 2009
- Publisher :
- Zenodo, 2009.
-
Abstract
- While coronaviruses were first identified nearly 60 years ago, they received notoriety in 2003 when one of their members was identified as the etiological agent of the Severe Acute Respiratory Syndrome (SARS-CoV) 1. Previously these viruses were known to be important agents of respiratory and enteric infections of domestic and companion animals and to cause approximately 15% of all cases of the common cold. This Review focuses on recent advances in our understanding of the mechanisms of coronavirus replication, interactions with the host immune response and disease pathogenesis and highlights the recent identification of numerous novel coronaviruses and the propensity of this virus family to cross species barriers.
- Subjects :
- medicine.medical_specialty
Coronaviridae
viruses
Biology
medicine.disease_cause
Severe Acute Respiratory Syndrome
Virus Replication
Microbiology
Models, Biological
Virus
Article
virus-host
Pathogenesis
03 medical and health sciences
Immune system
Medical microbiology
pathogen-host
medicine
Animals
Humans
biotic relations
Viridae
030304 developmental biology
Coronavirus
0303 health sciences
General Immunology and Microbiology
ComputingMilieux_THECOMPUTINGPROFESSION
030306 microbiology
biotic associations
corona viruses
Common cold
covid
pathogens
medicine.disease
biotic interaction
Virology
3. Good health
Infectious Diseases
TheoryofComputation_MATHEMATICALLOGICANDFORMALLANGUAGES
Viral replication
Parasitology
covid-19
TheoryofComputation_LOGICSANDMEANINGSOFPROGRAMS
Immunology
Coronavirus Infections
CETAF-taskforce
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Journal :
- Nature Reviews Microbiology
- Accession number :
- edsair.doi.dedup.....f3b9cefdd4ce176a6427333dd5925729