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Acid stress induces differential accumulation of metabolites in Escherichia coli O26:H11
- Source :
- Journal of applied microbiology.
- Publication Year :
- 2018
-
Abstract
- AIMS Acid exposure induces accumulation of certain metabolites in bacteria. The experimental objective was to identify the primary metabolites accumulating in Escherichia coli O26:H11 as a function of acid (pH 3·6) exposure. METHODS AND RESULTS Different buffers of pH 7·5 and 3·6 were used to study the metabolites accumulating in E. coli O26:H11 cells during such pH exposure. After 24 h of acid exposure, there was a 7-log decline in E. coli populations on trypticase soy agar plates. Untargeted metabolomic analysis identified 293 primary metabolites of which 145 metabolites were differentially (P
- Subjects :
- 0301 basic medicine
biology
Metabolite
030106 microbiology
Primary metabolite
General Medicine
Metabolism
biology.organism_classification
medicine.disease_cause
Applied Microbiology and Biotechnology
03 medical and health sciences
chemistry.chemical_compound
Metabolic pathway
030104 developmental biology
Metabolomics
chemistry
Biochemistry
medicine
Metabolome
Escherichia coli
Bacteria
Biotechnology
Subjects
Details
- ISSN :
- 13652672
- Database :
- OpenAIRE
- Journal :
- Journal of applied microbiology
- Accession number :
- edsair.doi.dedup.....f3e9cc319232d2ad91872316541e7432