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Impact of COVID‐19 in Liver Disease Progression
- Source :
- Hepatology Communications, Vol 5, Iss 7, Pp 1138-1150 (2021), Hepatology Communications
- Publication Year :
- 2021
- Publisher :
- Wiley, 2021.
-
Abstract
- Severe acute respiratory syndrome coronavirus‐2 (SARS‐CoV‐2) is a novel coronavirus that causes coronavirus disease 19 (COVID‐19), which has infected millions of people worldwide in only a few months. A minority, but significant number, of infected individuals require hospitalization and intensive care. From the start of this new virus pandemic, it was apparent that obese and/or diabetic individuals had a bad prognosis for COVID‐19 progression, strongly suggesting an association between liver disease and severe COVID‐19. Because chronic liver disease (CLD) is associated with immune dysregulation and inflammation, it is unsurprising that patients with CLD may carry a greater risk of adverse outcomes following SARS‐CoV‐2 infection. Initial COVID‐19 data have also indicated that healthy infected individuals display abnormal liver function tests, suggesting a possible direct implication of SARS‐CoV‐2 in liver damage. Here we show that COVID‐19 affects the liver metabolism and increases the morbidity and mortality of individuals with underlying CLD.<br />Chronic liver disease is associated with COVID‐19 severity and mortalityClinical indicators of liver disease can be prognostic markers of COVID‐19 severityLong‐term liver impact of COVID‐19 must not be neglected and warrants further investigation
- Subjects :
- Hepatology
business.industry
viruses
Reviews
Review
Disease
RC799-869
Immune dysregulation
Diseases of the digestive system. Gastroenterology
medicine.disease
medicine.disease_cause
Chronic liver disease
Virus
respiratory tract diseases
Liver disease
Intensive care
Immunology
medicine
Abnormal Liver Function Test
business
Coronavirus
Subjects
Details
- Language :
- English
- Volume :
- 5
- Issue :
- 7
- Database :
- OpenAIRE
- Journal :
- Hepatology Communications
- Accession number :
- edsair.doi.dedup.....f41a5be1528573b7d9fb67b826655c94