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X-linked Retinitis Pigmentosa Profile of Clinical Findings
- Source :
- Archives of Ophthalmology. 106:369-375
- Publication Year :
- 1988
- Publisher :
- American Medical Association (AMA), 1988.
-
Abstract
- An evaluation of 56 patients with X-linked retinitis pigmentosa revealed a profile of findings that include the following: night blindness within the first two decades of life; spherical refractive errors of -2.00 diopters or greater in addition to an increased prevalence of a cylindrical correction of +1.50 diopters or greater; appreciable impairment of central visual acuity to 20/200 or less by the fifth decade of life; characteristic patterns of field loss; presence of a foveal lesion in up to 75% of the study group; posterior subcapsular lens opacities; and nondetectable electroretinographic amplitudes in more than two thirds of the patients (using conventional full-field recording procedures). These observations are of general value in diagnosis of this disease and for counseling of patients afflicted with this severe form of hereditary night blindness.
- Subjects :
- Adult
Male
Fovea Centralis
medicine.medical_specialty
X Chromosome
Visual acuity
genetic structures
Fundus Oculi
Genetic Linkage
Eye disease
Visual Acuity
Cataract
Actuarial Analysis
Night Blindness
Ophthalmology
Retinitis pigmentosa
Electroretinography
medicine
Humans
Fluorescein Angiography
Child
Dioptre
medicine.diagnostic_test
business.industry
Retinitis pigmentosa GTPase regulator
Middle Aged
Refractive Errors
medicine.disease
eye diseases
Visual field
Child, Preschool
Visual Fields
medicine.symptom
business
Retinitis Pigmentosa
Retinopathy
Subjects
Details
- ISSN :
- 00039950
- Volume :
- 106
- Database :
- OpenAIRE
- Journal :
- Archives of Ophthalmology
- Accession number :
- edsair.doi.dedup.....f471ab2953680e3f2191cfae322f99cb
- Full Text :
- https://doi.org/10.1001/archopht.1988.01060130395029