Back to Search Start Over

Wing buds with three ZPAs

Authors :
Laurie E. Iten
Lorette C. Javois
Douglas J. Murphy
Source :
The Journal of experimental zoology. 215(1)
Publication Year :
1981

Abstract

It has been hypothesized that a diffusible morphogen emanates from the ZPA of the embryonic chick limb and that cells can have their presumptive fate respecified to form more posterior structures when exposed to a higher concentration of morphogen. Attempts to raise the concentration of morphogen by grafting two additional ZPAs into a host wing bud failed. Instead, the greater the positional disparity between the donor and host tissue at the graft sites, the greater the number of extra structures that formed.

Details

ISSN :
0022104X
Volume :
215
Issue :
1
Database :
OpenAIRE
Journal :
The Journal of experimental zoology
Accession number :
edsair.doi.dedup.....f4e7b82077f17a42370d48e3606ca895