Back to Search
Start Over
Brønsted base-catalyzed annulation of allyl ketones and alkynyl 1,2-diketones
- Source :
- Chemical Communications. 54:4266-4269
- Publication Year :
- 2018
- Publisher :
- Royal Society of Chemistry (RSC), 2018.
-
Abstract
- The discovery of new reaction modes mediated by easily available substrates is an important research topic in organic synthesis. Allyl ketones and related compounds have been demonstrated to undergo γ- or α-selective additions to different electrophiles. We disclose here the Brønsted base-catalyzed reaction of allyl ketones and alkynyl 1,2-diketones, which undergo a unique α-selective addition/intramolecular aldol-type annulation/C-C bond cleavage process, and a series of 2-acyloxycyclopent-3-enones can be obtained under very mild conditions.
- Subjects :
- Annulation
010405 organic chemistry
Chemistry
organic chemicals
Metals and Alloys
food and beverages
General Chemistry
010402 general chemistry
01 natural sciences
Medicinal chemistry
Catalysis
0104 chemical sciences
Surfaces, Coatings and Films
Electronic, Optical and Magnetic Materials
chemistry.chemical_compound
Important research
Intramolecular force
Electrophile
Materials Chemistry
Ceramics and Composites
Organic synthesis
Brønsted–Lowry acid–base theory
Bond cleavage
Subjects
Details
- ISSN :
- 1364548X and 13597345
- Volume :
- 54
- Database :
- OpenAIRE
- Journal :
- Chemical Communications
- Accession number :
- edsair.doi.dedup.....f52a9b27406b72a6396aca1cca287828