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Molecular Targets of Omega-3 Fatty Acids for Cancer Therapy

Molecular Targets of Omega-3 Fatty Acids for Cancer Therapy

Authors :
S. M. Nabavi
Maria Daglia
Gian Luigi Russo
K. Pandima Devi
Tamilselvam Rajavel
Seyed Fazel Nabavi
Pandima Devi, K
Rajavel, T.
Russo, G. L.
Daglia, M.
Nabavi, S. F.
Nabavi, S. M.
Source :
Scopus-Elsevier, Anti-cancer agents in medicinal chemistry, 15 (2015): 888–895., info:cnr-pdr/source/autori:Pandima Devi K.; Rajavel T.; Russo G.L.; Daglia M.; Nabavi S.F.; Nabavi S.M./titolo:Molecular targets of omega-3 fatty acids for cancer therapy/doi:/rivista:Anti-cancer agents in medicinal chemistry (Print)/anno:2015/pagina_da:888/pagina_a:895/intervallo_pagine:888–895/volume:15
Publication Year :
2015
Publisher :
Bentham Science Publishers Ltd., 2015.

Abstract

Nowadays, dietary guidelines acknowledge the therapeutic role of omega-3 polyunsaturated fatty acids, as the most important class of fatty acids, against different human diseases. During the last two decades, the average level of consumption of omega-3 polyunsaturated fatty acids has increased from 0.1 to 0.2 g per day. Omega-3 polyunsaturated fatty acids are a group of long-chain polyunsaturated fatty acids which are identified in different foods such as fatty fish, shellfish, and vegetable oils. A growing body of epidemiological and experimental evidence supports the anticancer effects of omega-3 polyunsaturated fatty acids, which led to the identification of their molecular targets in several cancer models. The present review focuses on the basic evidence supporting the potential applications of omega-3 polyunsaturated fatty acids in cancer therapy.

Details

ISSN :
18715206
Volume :
15
Database :
OpenAIRE
Journal :
Anti-Cancer Agents in Medicinal Chemistry
Accession number :
edsair.doi.dedup.....f56312edea837280190380e35dd228b8
Full Text :
https://doi.org/10.2174/1871520615666150424124606