Back to Search
Start Over
Quantitative and Qualitative Analysis of Micronuclei in the Buccal Mucosal Cells of Individuals Associated with Tobacco
- Source :
- MAMC Journal of Medical Sciences, Vol 4, Iss 1, Pp 12-17 (2018)
- Publication Year :
- 2018
- Publisher :
- Wolters Kluwer Medknow Publications, 2018.
-
Abstract
- Introduction: Micronucleus/micronuclei) have the potential to serve as an important biomarker in exfoliated cell. Exfoliated buccal mucosal cells can be evaluated using MN assay which can be applied to individuals practicing tobacco habits and are at risk of developing oral cancer. Material and Methods: 80 tobacco users and 20 non tobacco users as control were included in the study. Smears were taken and stained with H&E, feulgen, acridine orange. MN was counted using criteria given by Tolbert et al. Data was analyzed using SPSS software. Results: MN higher in tobacco users. The values obtained for the MN count in tobacco chewers using these stains were statistically significant (P
- Subjects :
- 0301 basic medicine
business.industry
Acridine orange
lcsh:R
lcsh:Medicine
Buccal mucosa cells
Buccal administration
Molecular biology
Stain
03 medical and health sciences
chemistry.chemical_compound
030104 developmental biology
0302 clinical medicine
chemistry
030220 oncology & carcinogenesis
micronuclei
Micronucleus test
Fluorescence microscope
Medicine
Feulgen stain
business
Micronucleus
cytogenic biomarker
Carcinogen
Subjects
Details
- Language :
- English
- ISSN :
- 23947438
- Volume :
- 4
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- MAMC Journal of Medical Sciences
- Accession number :
- edsair.doi.dedup.....f57631dcd2e7fc9813d89d3ae6e44e51