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Deep brain stimulation for parkinson's disease: correlation between intraoperative subthalamic nucleus neurophysiology and most effective contacts
- Source :
- Stereotactic and functional neurosurgery. 80(1-4)
- Publication Year :
- 2004
-
Abstract
- Though intraoperative neurophysiology is essential to precisely define the definitive target, little is known regarding its predictive value in defining the most effective contact for chronic deep brain stimulation. In this retrospective study, we reviewed the correlation between intraoperative neurophysiology and contacts selected for chronic stimulation. Twenty consecutive patients implanted for subthalamic nucleus (STN) stimulation were reviewed. There was no significant correlation between the electrophysiologically defined STN and the most effective contact for chronic stimulation at 3 months or at 6 months. Furthermore, there was a discrepancy between the most effective contact for rigidity versus akinesia or tremor at 3 months. Interestingly, at 3 months, the same electrode contact was maximally efficient for rigidity, akinesia and tremor in only 13 of the 39 cases. This lack of correlation did not affect the global improvement.
- Subjects :
- Adult
Male
medicine.medical_specialty
Deep brain stimulation
Parkinson's disease
medicine.medical_treatment
Stimulation
Electric Stimulation Therapy
Electrode Contact
Neurosurgical Procedures
Correlation
Subthalamic Nucleus
medicine
Humans
Aged
Parkinson Disease
Neurophysiology
Middle Aged
medicine.disease
Predictive value
Surgery
Electrodes, Implanted
Subthalamic nucleus
Treatment Outcome
Anesthesia
Female
Neurology (clinical)
Psychology
Subjects
Details
- ISSN :
- 10116125
- Volume :
- 80
- Issue :
- 1-4
- Database :
- OpenAIRE
- Journal :
- Stereotactic and functional neurosurgery
- Accession number :
- edsair.doi.dedup.....f5a6c6dc624223dfa07a4bcdbb5f1444