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Properties of Extracellular Products Produced by Group A Streptococci Isolated from Patients with Streptococcal Toxic Shock Syndrome
- Source :
- Journal of the Japanese Association for Infectious Diseases. 71:1187-1192
- Publication Year :
- 1997
- Publisher :
- The Japanese Association for Infectious Diseases, 1997.
-
Abstract
- Extracellular products of group A streptococci isolated from patients with streptococcal toxic shock syndrome (STSS) were examined. The outline of the discussion of the 3 products are as follows; streptolysin O (SLO), proteinase and erythrogenic toxin. SLO and proteinase showed a relatively large amount of products more than erythrogenic toxin. SLO produced by group A streptococci isolated from the patient with STSS had an isoelectric point (pI) of 6.0 and a molecular weight of 64,000 and showed hemolytic activity in the presence of 2-mercaptoethanol (2-ME). Furthermore, the hemolytic activities of all components were inhibited by gamma-globulin and cholesterol. Proteinase had pIs of 8.7 and 8.9, and a molecular weight of 21,000. These data suggest that STSS clinical criteria probably reflects a characteristic of a large amount of products of individual S. pyogenes isolates.
Details
- ISSN :
- 1884569X and 03875911
- Volume :
- 71
- Database :
- OpenAIRE
- Journal :
- Journal of the Japanese Association for Infectious Diseases
- Accession number :
- edsair.doi.dedup.....f5aae3e94f9c86fce219587c919d4375
- Full Text :
- https://doi.org/10.11150/kansenshogakuzasshi1970.71.1187