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Diagnosis, Prognosis, and Therapy of Transthyretin Amyloidosis
- Source :
- Journal of the American College of Cardiology. 66(21):2451-2466
- Publication Year :
- 2015
- Publisher :
- Elsevier BV, 2015.
-
Abstract
- Transthyretin amyloidosis is a fatal disorder that is characterized primarily by progressive neuropathy and cardiomyopathy. It occurs in both a mutant form (with autosomal dominant inheritance) and a wild-type form (with predominant cardiac involvement). This article guides clinicians as to when the disease should be suspected, describes the appropriate diagnostic evaluation for those with known or suspected amyloidosis, and reviews the interventions currently available for affected patients.
- Subjects :
- medicine.medical_specialty
Pathology
medicine.medical_treatment
Cardiomyopathy
Disease
Diagnostic evaluation
Liver transplantation
familial amyloid cardiomyopathy
Familial amyloid cardiomyopathy
liver transplantation
medicine
Animals
Humans
genetics
Amyloid Neuropathies, Familial
biology
business.industry
Amyloidosis
Prognosis
medicine.disease
Dermatology
Transthyretin
familial amyloid polyneuropathy
biology.protein
Cardiomyopathies
business
Cardiology and Cardiovascular Medicine
Attr amyloidosis
Subjects
Details
- ISSN :
- 07351097
- Volume :
- 66
- Issue :
- 21
- Database :
- OpenAIRE
- Journal :
- Journal of the American College of Cardiology
- Accession number :
- edsair.doi.dedup.....f68569280ba91e565bbc201ba46b007e
- Full Text :
- https://doi.org/10.1016/j.jacc.2015.09.075