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Maladaptive compensation of right fusiform gyrus in developmental dyslexia: A hub-based white matter network analysis
- Source :
- Cortex, Cortex, Elsevier, 2021, 145, pp.57-66. ⟨10.1016/j.cortex.2021.07.016⟩
- Publication Year :
- 2021
- Publisher :
- HAL CCSD, 2021.
-
Abstract
- International audience; Cognitive theories have been proposed to clarify the causes and symptoms of dyslexia. However, correlations between local network parameters of white matter connectivity and literacy skills remain poorly known. An unbiased hypothesis-free approach was adopted to examine the correlations between literacy symptoms (reading and spelling) and hub-based white matter networks' connectivity parameters [nodal degree fractional anisotropy (FA) values] of 90 brain regions based on Anatomical Atlas Labels (AAL) in a group of French children with dyslexia aged 9–14 years. Results revealed that the higher the right fusiform gyrus's (FFG) nodal degree FA values, the lower the reading accuracy for words and pseudowords in dyslexic children. The results indicate that the severity of word/pseudoword reading symptoms in dyslexia relates to a white matter network centered around the right FFG. The negative correlation between right FFG network connectivity and reading accuracy, in particular pseudoword reading accuracy, suggests that right FFG represents a maladaptive compensation towards a general orthography-to-phonology decoding ability in developmental dyslexia.
- Subjects :
- Cognitive Neuroscience
media_common.quotation_subject
Developmental dyslexia
White matter network
Experimental and Cognitive Psychology
Literacy skills
050105 experimental psychology
White matter
Dyslexia
03 medical and health sciences
0302 clinical medicine
Reading (process)
Fractional anisotropy
medicine
Humans
0501 psychology and cognitive sciences
Child
media_common
Fusiform gyrus
05 social sciences
Brain
[SDV.NEU.SC]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Cognitive Sciences
Cognition
medicine.disease
White Matter
Spelling
Temporal Lobe
Pseudoword
Neuropsychology and Physiological Psychology
medicine.anatomical_structure
Reading
Psychology
030217 neurology & neurosurgery
Cognitive psychology
Subjects
Details
- Language :
- English
- ISSN :
- 00109452
- Database :
- OpenAIRE
- Journal :
- Cortex, Cortex, Elsevier, 2021, 145, pp.57-66. ⟨10.1016/j.cortex.2021.07.016⟩
- Accession number :
- edsair.doi.dedup.....f69414d57f3391c59e89495624bca9b8