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Prescription refill, patient self-report and physician report in assessing adherence to oral endocrine therapy in early breast cancer patients: a restrospective cohort study in Catalonia, Spain
- Source :
- Recercat. Dipósit de la Recerca de Catalunya, instname, British Journal of Cancer, Dipòsit Digital de la UB, Universidad de Barcelona, BRITISH JOURNAL OF CANCER, r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau, Universitat Politècnica de Catalunya (UPC)
- Publisher :
- Cancer Research UK
-
Abstract
- AIMS: To compare different methods in order to assess adherence and persistence with oral endocrine therapy in women diagnosed with breast cancer (BC) in Catalonia. MATERIALS AND METHODS: This study covered all women newly diagnosed with stage I, II or IIIa BC and positive hormone receptors at six hospitals in Catalonia (Spain) in 2004. Adherence was assessed on the basis of physician report and patient self-report using a telephone questionnaire. Persistence was measured by refill prescriptions. We used the Kappa index to compare adherence measures and logistic regression to evaluate adherence-related risk factors. RESULTS: The study covered a total of 692 women. Adherence ranged from 92% (self-report) to 94.7% (physician report), depending on the measure used; persistence was 74.7% at 5 years of follow-up. Low concordance between measures was observed (Kappa range: 0.018-0.267). Patients aged 50-74 years showed higher adherence than those aged
- Subjects :
- Cancer Research
medicine.medical_specialty
Catalonia
Antineoplastic Agents, Hormonal
Alternative medicine
MEDLINE
Administration, Oral
Breast Neoplasms
Drug Prescriptions
Medication Adherence
Càncer de mama
Breast cancer
Patient Self-Report
Risk Factors
Internal medicine
medicine
Humans
adherence
Medical prescription
early breast cancer
Self report
Hormone therapy
Early breast cancer
Aged
Retrospective Studies
business.industry
endocrine therapy
Endocrine therapy
Retrospective cohort study
Catalunya
persistence
Middle Aged
humanities
Surgery
Oncology
Spain
Clinical Study
Female
Self Report
business
Hormonoteràpia
Subjects
Details
- ISSN :
- 00070920
- Database :
- OpenAIRE
- Journal :
- Recercat. Dipósit de la Recerca de Catalunya, instname, British Journal of Cancer, Dipòsit Digital de la UB, Universidad de Barcelona, BRITISH JOURNAL OF CANCER, r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau, Universitat Politècnica de Catalunya (UPC)
- Accession number :
- edsair.doi.dedup.....f6c6a19a30b0ca83cd0a6605d15908a1