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Improved clinical outcomes for multiple myeloma patients treated at a single specialty clinic
- Source :
- Annals of Hematology. 96:441-448
- Publication Year :
- 2016
- Publisher :
- Springer Science and Business Media LLC, 2016.
-
Abstract
- Despite recent advances made in its treatment, multiple myeloma (MM) remains an incurable B cell malignancy. Thus, the objective for treating these patients is to prolong overall survival (OS) and preserve patients’ quality of life. We have analyzed data from 264 consecutive MM patients who had their initial visit between July 1, 2004 and December 1, 2014 and have received treatment in a single clinic specializing in MM. We determined their progression-free survival (PFS, OS, and 5-year OS). The PFS for frontline (n = 165 treatments), salvage (n = 980), and all treatments (n = 1145) were 13.9, 4.6, and 5.5 months, respectively. The median OS of all patients was 98 months with a 5-year survival of 74%. The results of this study show a marked improvement in OS for unselected MM patients compared with historical data. There were no significant differences in OS between patients with different International Staging System (ISS) stages. Younger patients (
- Subjects :
- Adult
Male
medicine.medical_specialty
Outpatient Clinics, Hospital
Specialty
Bortezomib
03 medical and health sciences
0302 clinical medicine
Initial visit
Quality of life
Internal medicine
Antineoplastic Combined Chemotherapy Protocols
medicine
Overall survival
Humans
Lenalidomide
Staging system
B cell malignancy
Multiple myeloma
Aged
Retrospective Studies
Aged, 80 and over
business.industry
Hematology
General Medicine
Middle Aged
medicine.disease
Thalidomide
Surgery
Survival Rate
030220 oncology & carcinogenesis
Female
Multiple Myeloma
business
Oligopeptides
Follow-Up Studies
030215 immunology
Subjects
Details
- ISSN :
- 14320584 and 09395555
- Volume :
- 96
- Database :
- OpenAIRE
- Journal :
- Annals of Hematology
- Accession number :
- edsair.doi.dedup.....f6d95538342b7be649b39819fca0423e