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Lack of Evidence of Sylvatic Transmission of Dengue Viruses in the Amazon Rainforest Near Iquitos, Peru
- Source :
- Vector Borne Zoonotic Dis
- Publication Year :
- 2019
- Publisher :
- Mary Ann Liebert Inc, 2019.
-
Abstract
- Dengue viruses (DENV) are currently responsible for more human morbidity and mortality than any other known arbovirus, and all four DENV are known to exist in sylvatic cycles that might allow these viruses to persist if the urban (Aedes aegypti) cycle could be controlled. To determine whether DENV were being maintained in a sylvatic cycle in a forested area about 14 km southwest of Iquitos, Peru, a city in which all 4 serotypes of DENV circulate, we placed 20 DENV seronegative Aotus monkeys in cages either in the canopy or near ground level for a total of 125.6 months. Despite capturing >66,000 mosquitoes in traps that collected some of the mosquitoes attracted to these monkeys, blood samples obtained once a month from each animal were tested and found to be negative by an enzyme-linked immunosorbent assay for IgM and IgG antibodies to dengue, yellow fever, Venezuelan equine encephalitis, Oropouche, and Mayaro viruses. Although all four DENV serotypes were endemic in nearby Iquitos, the findings of this study did not support a DENV sylvatic maintenance and transmission cycle in a selected area of the Amazon rainforest in northeastern Peru.
- Subjects :
- 0301 basic medicine
Rainforest
viruses
030231 tropical medicine
Aedes aegypti
Microbiology
Arbovirus
Dengue fever
law.invention
03 medical and health sciences
0302 clinical medicine
law
Virology
parasitic diseases
Peru
medicine
Animals
biology
Amazon rainforest
virus diseases
Transmission cycle
Original Articles
Dengue Virus
biochemical phenomena, metabolism, and nutrition
030108 mycology & parasitology
biology.organism_classification
medicine.disease
Human morbidity
Culicidae
Infectious Diseases
Transmission (mechanics)
Sentinel Species
Aotidae
Sentinel Surveillance
Subjects
Details
- ISSN :
- 15577759 and 15303667
- Volume :
- 19
- Database :
- OpenAIRE
- Journal :
- Vector-Borne and Zoonotic Diseases
- Accession number :
- edsair.doi.dedup.....f71822ae2b7ec25686b68ee573765b86