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Stenting deferral in primary percutaneous coronary intervention: exploring benefits and suitable interval in heavy thrombus burden
- Source :
- The Egyptian Heart Journal, Vol 73, Iss 1, Pp 1-9 (2021)
- Publication Year :
- 2021
- Publisher :
- SpringerOpen, 2021.
-
Abstract
- Background Deferred stenting, despite being successful in early studies, showed no benefit in recent trials. However, these trials were testing routine deferral; not in patients with heavy thrombus burden. Results This is a prospective, Randomized Clinical Trial that included 150 patients who presented with STEMI, patients were allocated into three equal groups after the coronary angiography ± primary intervention and before stenting of the culprit lesion; group (A) included 50 patients with early deferral of stenting, group (B) included 50 patients with late deferral and group (C) included 50 patients with immediate stenting. No-reflow was significantly higher in group C, while Final TIMI flow grade 3 and MBG grade 3 were significantly higher in group A and B than group C; p = 0.019 and p p = 0.029). Conclusions Stent deferral was proved to be better than immediate stenting after recanalization of IRA, in achieving TIMI III flow, reducing risk of 6 months MACE, and restoration of myocardial function in a subset of STEMI patients presenting with large thrombus burden. While, no significant difference was found between both deferral times in final TIMI flow, or clinical outcomes.
- Subjects :
- medicine.medical_specialty
Slow-flow
medicine.medical_treatment
ST-segment elevation
No-reflow
Group B
law.invention
Randomized controlled trial
law
Internal medicine
medicine
Diseases of the circulatory (Cardiovascular) system
Myocardial infarction
cardiovascular diseases
Thrombus
business.industry
Percutaneous coronary intervention
Stent
medicine.disease
surgical procedures, operative
RC666-701
Cardiology
business
Deferral
Mace
TIMI
Subjects
Details
- Language :
- English
- Volume :
- 73
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- The Egyptian Heart Journal
- Accession number :
- edsair.doi.dedup.....f729dafb85c15e4589e6626296d26710