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An Evidence-Based Proposal for Predicting Organ Failure in Severe Acute Pancreatitis
- Source :
- Pancreas. 42:1255-1261
- Publication Year :
- 2013
- Publisher :
- Ovid Technologies (Wolters Kluwer Health), 2013.
-
Abstract
- Early, efficient, and accurate evaluation for organ failure is an important step for improving outcome in severe acute pancreatitis (SAP). We aim to develop a method that can early, efficiently, and accurately evaluate the in-hospital organ failure in patients with SAP.Using multivariate logistic regression analysis, the associative factors for in-hospital organ failure were evaluated retrospectively from conventional data obtained from 393 patients with SAP from 2000 to 2012. In classification and regression tree analysis, a new clinical scoring system was developed for the evaluation of in-hospital organ failure in SAP. We also compared the accuracy of our new scoring system with multiple organ dysfunction score and Acute Physiology and Chronic Health Examination II score by the receiver operating characteristic curve.Laboratory results revealed serum calcium level greater than or equal to 1.84 mmol/L, serum creatinine level greater than or equal to 110 µmol/L, age greater than or equal to 72 years, activated partial thromboplastin time less than or equal to 30.95 seconds, and Balthazar computed tomography score greater than or equal to 7 (CCAAB) score system, each contributed 1 point for the prediction of organ failure. The area under the curve of the CCAAB score system was similar to multiple organ dysfunction scores and Acute Physiology and Chronic Health Examination II scores.The new scoring system CCAAB is an efficient and accurate method for the early evaluation of patients with SAP for in-hospital organ failure.
- Subjects :
- Adult
Male
medicine.medical_specialty
Evidence-based practice
genetic structures
Multiple Organ Failure
Endocrinology, Diabetes and Metabolism
Severity of Illness Index
Young Adult
Endocrinology
Internal Medicine
medicine
Humans
In patient
Intensive care medicine
Aged
Retrospective Studies
Aged, 80 and over
Inpatients
Evidence-Based Medicine
Hepatology
business.industry
Middle Aged
Creatine
Prognosis
medicine.disease
Early Diagnosis
Logistic Models
Pancreatitis
ROC Curve
Acute Disease
Multivariate Analysis
Acute pancreatitis
Calcium
Female
Tomography, X-Ray Computed
business
Subjects
Details
- ISSN :
- 08853177
- Volume :
- 42
- Database :
- OpenAIRE
- Journal :
- Pancreas
- Accession number :
- edsair.doi.dedup.....f77a2f6b2f02891c4eb1b8eff7330cc4