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Spectral, Thermal and In Vitro Antibacterial Studies on Cadmium(II)– bis(2,2/-methylidenephenol)diaminoethane
- Source :
- Volume: 5, Issue: 3 1029-1036, Journal of the Turkish Chemical Society Section A: Chemistry, Journal of the Turkish Chemical Society, Section A: Chemistry, Vol 5, Iss 3, Pp 1029-1036 (2018)
- Publication Year :
- 2018
- Publisher :
- The Turkish Chemical Society, 2018.
-
Abstract
- The objective of this work is to prepare a new synthetic protocol of the cadmium(II) complex of bis(2,2’-methylylidenephenol)diaminoethane (H2BMPDE) and study the antimicrobial bioefficacy. In this work, we report the extractive method for the synthesis of cadmium(II) complex of bis(2,2’-methylidenephenol)diaminoethane from salicylaldehyde, ethylenediamine, hydrochloric acid, and cadmium sulfate in a single, simple step. The ligand and the complex were characterized by FTIR, UV-Vis, 1H and 13C NMR, magnetic moment, GC-MS, thermal and elemental analysis. The chemical data indicated the formation of 1:1 (metal:ligand) mole ratio and distorted tetrahedral geometry was suggested as based on spectral data and magnetic moment. The results of preliminary antibacterial study revealed that Cd(II) H2BMPDE complexes prepared from different acids (HCl, HNO3, H2SO4) were effective against clinically important Gram-negative bacteria (Escherichia coli, pseudomonas, Klebsiella ) and Gram-positive bacterium (Staphylococcus aureus).The result indicated a new synthetic protocol for the synthesis of H2BMPDE complexes. On the application, H2BMPDE and its complexes could be considered as a potential antibacterial agent with further investigative analysis.
- Subjects :
- Cadmium sulfate
chemistry.chemical_element
Ethylenediamine
010402 general chemistry
01 natural sciences
lcsh:Chemistry
chemistry.chemical_compound
antimicrobial bioefficacy
stability studies,Cadmium H2BMPDE,physicochemical studies,antimicrobial bioefficacy
Electrochemistry
Antibacterial agent
Cadmium
010405 organic chemistry
Ligand
stability studies
Tetrahedral molecular geometry
physicochemical studies
General Chemistry
Carbon-13 NMR
Elektrokimya
0104 chemical sciences
lcsh:QD1-999
chemistry
Salicylaldehyde
Cadmium H2BMPDE
Nuclear chemistry
Subjects
Details
- ISSN :
- 21490120
- Volume :
- 5
- Database :
- OpenAIRE
- Journal :
- Journal of the Turkish Chemical Society Section A: Chemistry
- Accession number :
- edsair.doi.dedup.....f8538b441e247239029ccfd3e2e90c69