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Immune adherence with keratinized human oral mucosa and human serum
- Source :
- Scandinavian journal of dental research. 79(1)
- Publication Year :
- 1971
-
Abstract
- – All normal human sera examined have been shown to contain complement-fixing antibody to an antigen present in stratum corneum of human skin. By immune adherence with human sera and sections of frozen biopsy specimens, the antigen was found to be present in sections of keratotic and parakeratotic areas of human gingiva, tongue, alveolar, buccal, and palatal mucosa. Serum from biopsy donors mediated the adherence reaction. Absorption with a phenol-water extract (water phase) of stratum corneum of skin removed the antibodies. The antigen was not detected in non-keratinized areas of human oral mucosa, including gingival crevice and cuff epithelium. Erythrocytes also adhered to keratinized epithelium in gingival biopsy specimens fixed in ethanol and cleared in xylene at 4° C prior to sectioning and incubation with human serum.
- Subjects :
- Pathology
medicine.medical_specialty
Erythrocytes
Time Factors
Biopsy
Gingiva
Human skin
Biology
In Vitro Techniques
Antibodies
Antigen
Tongue
medicine
Stratum corneum
Methods
Humans
Oral mucosa
Antigens
General Dentistry
Immune adherence reaction
Skin
integumentary system
medicine.diagnostic_test
Palate
Complement Fixation Tests
Immune adherence
Mouth Mucosa
Buccal administration
Immune Adherence Reaction
medicine.anatomical_structure
Blood
Immunology
Keratins
Subjects
Details
- ISSN :
- 0029845X
- Volume :
- 79
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- Scandinavian journal of dental research
- Accession number :
- edsair.doi.dedup.....f86a63a9a8db2352079c817fc02a2aa3