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Durability of the St. Jude Epic Supra Bioprosthetic Valve in the Pulmonary Position
- Source :
- Seminars in thoracic and cardiovascular surgery. 33(1)
- Publication Year :
- 2020
-
Abstract
- Epic Supra valves have been used off-label in the pulmonary position. We aim to evaluate the durability of Epic valves in the pulmonary position. We performed a retrospective review of all Epic valves placed in the pulmonary position from October 2008 to May 2019. Time-to-event analysis was performed using Kaplan-Meier estimates to evaluate freedom from valve intervention, moderate pulmonary regurgitation, and peak velocity greater than 3.5 m/s. Valve dysfunction was a composite of all 3 end points. A total of 79 patients had Epic valves implanted in the pulmonary position. Median age was 18.5 years (15thβ85th percentile 11.2β41.0). In total, 1 (1%) 19 mm valve, 4 (5%) 21 mm valves, 8 (10%) 23 mm valves, 23 (29%) 25 mm valves, and 43 (54%) 27 mm valves were implanted. There were no deaths or transplants. Median follow-up was 3.1 years (interquartile range 1.0β5.5). At 5 years, freedom from valve intervention was 95%, freedom from valve dysfunction was 68%, freedom from moderate pulmonary regurgitation was 73%, and freedom from peak velocity greater than 3.5 m/s was 82%. Epic Supra valves provide an acceptable valve replacement in the pulmonary position for children and adults. Longer follow-up is needed to determine valve durability through the entirety of the valve life expectancy.
- Subjects :
- Pulmonary and Respiratory Medicine
Adult
medicine.medical_specialty
Adolescent
medicine.medical_treatment
030204 cardiovascular system & hematology
EPIC
Prosthesis Design
Bioprosthetic valve
03 medical and health sciences
0302 clinical medicine
Valve replacement
Interquartile range
Pulmonary regurgitation
Medicine
Humans
Child
Retrospective Studies
Bioprosthesis
Heart Valve Prosthesis Implantation
Retrospective review
Pulmonary Valve
business.industry
General Medicine
Surgery
Prosthesis Failure
medicine.anatomical_structure
Treatment Outcome
030228 respiratory system
Peak velocity
Pulmonary valve
Aortic Valve
Heart Valve Prosthesis
Cardiology and Cardiovascular Medicine
business
Subjects
Details
- ISSN :
- 15329488
- Volume :
- 33
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- Seminars in thoracic and cardiovascular surgery
- Accession number :
- edsair.doi.dedup.....f87119865ee93640c3174f71b9b89020