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Durability of the St. Jude Epic Supra Bioprosthetic Valve in the Pulmonary Position

Authors :
Christopher A. Caldarone
Jeffrey S. Heinle
Athar M. Qureshi
Daniel J. Penny
Zachary A. Spigel
Huirong Zhu
Ziyad M. Binsalamah
Source :
Seminars in thoracic and cardiovascular surgery. 33(1)
Publication Year :
2020

Abstract

Epic Supra valves have been used off-label in the pulmonary position. We aim to evaluate the durability of Epic valves in the pulmonary position. We performed a retrospective review of all Epic valves placed in the pulmonary position from October 2008 to May 2019. Time-to-event analysis was performed using Kaplan-Meier estimates to evaluate freedom from valve intervention, moderate pulmonary regurgitation, and peak velocity greater than 3.5 m/s. Valve dysfunction was a composite of all 3 end points. A total of 79 patients had Epic valves implanted in the pulmonary position. Median age was 18.5 years (15th–85th percentile 11.2–41.0). In total, 1 (1%) 19 mm valve, 4 (5%) 21 mm valves, 8 (10%) 23 mm valves, 23 (29%) 25 mm valves, and 43 (54%) 27 mm valves were implanted. There were no deaths or transplants. Median follow-up was 3.1 years (interquartile range 1.0–5.5). At 5 years, freedom from valve intervention was 95%, freedom from valve dysfunction was 68%, freedom from moderate pulmonary regurgitation was 73%, and freedom from peak velocity greater than 3.5 m/s was 82%. Epic Supra valves provide an acceptable valve replacement in the pulmonary position for children and adults. Longer follow-up is needed to determine valve durability through the entirety of the valve life expectancy.

Details

ISSN :
15329488
Volume :
33
Issue :
1
Database :
OpenAIRE
Journal :
Seminars in thoracic and cardiovascular surgery
Accession number :
edsair.doi.dedup.....f87119865ee93640c3174f71b9b89020