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Human Exosomes Accelerate Cutaneous Wound Healing by Promoting Collagen Synthesis in a Diabetic Mouse Model
- Source :
- Stem Cells and Development. 30:922-933
- Publication Year :
- 2021
- Publisher :
- Mary Ann Liebert Inc, 2021.
-
Abstract
- Chronic wounds including diabetic foot ulcers are clinical emergencies that need careful management. Exosomes from human adipose-derived mesenchymal stem cells (hADSCs-Ex) are a new promising cell-free therapy for the regeneration of dermal wounds. We established a delayed wound healing model using diabetic female mice. A 1.5 cm
- Subjects :
- 0301 basic medicine
Cell
Biology
Exosomes
Mice
03 medical and health sciences
0302 clinical medicine
Diabetes mellitus
Diabetes Mellitus
medicine
Animals
Humans
Skin
Wound Healing
Mesenchymal stem cell
Diabetic mouse
Cell Biology
Hematology
medicine.disease
Diabetic foot
Diabetic Foot
Microvesicles
030104 developmental biology
medicine.anatomical_structure
Cancer research
Female
Collagen
Cutaneous wound
Wound healing
030217 neurology & neurosurgery
Developmental Biology
Subjects
Details
- ISSN :
- 15578534 and 15473287
- Volume :
- 30
- Database :
- OpenAIRE
- Journal :
- Stem Cells and Development
- Accession number :
- edsair.doi.dedup.....f8a74915a7281ad0e8a53d0aaeec3dbe
- Full Text :
- https://doi.org/10.1089/scd.2021.0100