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Human Exosomes Accelerate Cutaneous Wound Healing by Promoting Collagen Synthesis in a Diabetic Mouse Model

Authors :
Jing Zhang
Yang Zhou
Yuanlin Zhang
Yi-jun Lu
Bo Zhao
Shou-Tao Lu
Jun Zhang
Xingliao Zhang
Yu Fu
Wanting Zhang
Source :
Stem Cells and Development. 30:922-933
Publication Year :
2021
Publisher :
Mary Ann Liebert Inc, 2021.

Abstract

Chronic wounds including diabetic foot ulcers are clinical emergencies that need careful management. Exosomes from human adipose-derived mesenchymal stem cells (hADSCs-Ex) are a new promising cell-free therapy for the regeneration of dermal wounds. We established a delayed wound healing model using diabetic female mice. A 1.5 cm

Details

ISSN :
15578534 and 15473287
Volume :
30
Database :
OpenAIRE
Journal :
Stem Cells and Development
Accession number :
edsair.doi.dedup.....f8a74915a7281ad0e8a53d0aaeec3dbe
Full Text :
https://doi.org/10.1089/scd.2021.0100