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Fear of Progression is Determined by Anxiety and Self-Efficacy but not Disease-Specific Parameters in Patients with Parkinson’s Disease: Preliminary Data from a Multicenter Cross-Sectional Study

Authors :
Ann-Kristin, Folkerts
Lena, Haarmann
Jörn, Nielsen
Jochen, Saliger
Mareike, Eschweiler
Hans, Karbe
Niels, Allert
Viktoria, Vida
Claudia, Trenkwalder
Annika, Kruse
Henriette, Oelsner
Georg, Ebersbach
Elke, Kalbe
Source :
Journal of Parkinson's Disease. 12:2543-2553
Publication Year :
2022
Publisher :
IOS Press, 2022.

Abstract

Background: Fear of progression (FoP) is a reactive, conscious concern about chronic disease progression and its consequences which may limit quality of life substantially. Only one study has examined FoP in Parkinson’s disease (PD), showing the second highest FoP scores among chronic diseases. Objective: To examine FoP prevalence and to exploratorily analyze determinants of FoP in PD. Methods: Within a multicenter cross-sectional study, 120 PD inpatients (age: 64.45±9.20; 60.8% male; UPDRS-III: 28.86±16.12) were examined with the FoP questionnaire (FoP-Q; max. 20 points). Stepwise multiple linear regression analysis examined sociodemographic, clinical, and (neuro-) psychological determinants of FoP. Results: With a mean FoP-Q score of 8.08±2.17, 63.0% of the patients were classified with moderate FoP and 17.6% with dysfunctional (i.e., severe) FoP. The highest scores were shown for the subscale ‘loss of autonomy’. Increased levels of anxiety, less self-efficacy, female gender, current employment, and lower health literacy were identified as significant determinants associated with FoP. Conclusion: With more than 80% of patients showing moderate to dysfunctional FoP, it must be regarded as a frequent symptom in PD, which needs to be further understood and addressed in clinical practice. Clinical parameters like PD duration and severity were no determinants for FoP, indicating that FoP awareness must be considered by professionals at all disease stages.

Details

ISSN :
1877718X and 18777171
Volume :
12
Database :
OpenAIRE
Journal :
Journal of Parkinson's Disease
Accession number :
edsair.doi.dedup.....f8fc2655203ee53e7fb77c3b4915c8ba
Full Text :
https://doi.org/10.3233/jpd-223314