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Impact of Toll-like Receptors 2(TLR2) and TLR 4 Gene Variations on HCV Susceptibility, Response to Treatment and Development of Hepatocellular Carcinoma in Cirrhotic HCV Patients
- Source :
- Immunological Investigations. 49:462-476
- Publication Year :
- 2019
- Publisher :
- Informa UK Limited, 2019.
-
Abstract
- Background and Aims: Genetic polymorphisms of Toll-like receptors (TLRs) have been proposed to affect susceptibility to HCV infection and progression to end-stage liver disease. This study was cond...
- Subjects :
- Liver Cirrhosis
0301 basic medicine
Carcinoma, Hepatocellular
Immunology
Interferon alpha-2
Antiviral Agents
Polymorphism, Single Nucleotide
03 medical and health sciences
Liver disease
0302 clinical medicine
Humans
Medicine
Genetic Predisposition to Disease
Receptor
Gene
Alleles
biology
business.industry
Liver Neoplasms
General Medicine
medicine.disease
Hepatitis C
Response to treatment
Toll-Like Receptor 2
Toll-Like Receptor 4
TLR2
Treatment Outcome
030104 developmental biology
Haplotypes
030220 oncology & carcinogenesis
Hepatocellular carcinoma
Toll
biology.protein
RNA, Viral
business
Subjects
Details
- ISSN :
- 15324311 and 08820139
- Volume :
- 49
- Database :
- OpenAIRE
- Journal :
- Immunological Investigations
- Accession number :
- edsair.doi.dedup.....f929d01369832e39afe410a18b2f20b2