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Medicines used in respiratory diseases only seen in children
- Source :
- The European respiratory journal. 34(3)
- Publication Year :
- 2009
-
Abstract
- Detailed literature searches were carried out in seven respiratory disease areas. Therapeutic evidence for efficacy of medicinal products was assessed using the Grades of Recommendation, Assessment and Evaluation (GRADE) methodology, as well as an assessment of safety and side-effects. Systemic corticosteroids may reduce the development of bronchopulmonary dysplasia but have serious side-effects. Antioxidants need further study to demonstrate whether they have long-term benefits. Treatments for acute bronchiolitis have shown little benefit but new antiviral and monoclonal antibodies need further assessment. Well-constructed studies are needed to confirm the value of inhaled corticosteroids and/or montelukast in the management of viral-induced wheeze. Corticosteroids are the treatment of choice in croup. Minimal or no information is available for the treatment of congenital lung abnormalities, bronchiolitis obliterans and interstitial lung disease.
- Subjects :
- Pulmonary and Respiratory Medicine
BIRTH-WEIGHT INFANTS
Lung Diseases
medicine.medical_specialty
croup
Placebo-controlled study
Anti-Inflammatory Agents
Respiratory System Agents
Bronchiolitis obliterans
Infant, Premature, Diseases
PLACEBO-CONTROLLED TRIAL
viral-induced wheeze
Antioxidants
VITAMIN-A SUPPLEMENTATION
Wheeze
bronchopulmonary dysplasia
medicine
Humans
PULMONARY ALVEOLAR PROTEINOSIS
Bronchiolitis * bronchiolitis obliterans * bronchopulmonary dysplasia * croup * interstitial lung disease * viral-induced wheeze
Intensive care medicine
Child
Montelukast
interstitial lung disease
business.industry
POSTINFECTIOUS BRONCHIOLITIS OBLITERANS
Interstitial lung disease
Age Factors
Infant, Newborn
Infant
RANDOMIZED CONTROLLED-TRIAL
medicine.disease
Anti-Bacterial Agents
Bronchopulmonary dysplasia
INHALED NITRIC-OXIDE
Bronchiolitis
CHRONIC LUNG-DISEASE
Croup
Child, Preschool
medicine.symptom
business
SYNCYTIAL VIRUS-INFECTION
CHRONIC BRONCHOPULMONARY DYSPLASIA
bronchiolitis obliterans
Infant, Premature
medicine.drug
Subjects
Details
- Language :
- English
- ISSN :
- 13993003 and 09031936
- Volume :
- 34
- Issue :
- 3
- Database :
- OpenAIRE
- Journal :
- The European respiratory journal
- Accession number :
- edsair.doi.dedup.....f958ef7a1d123c02096df4d77bfec844