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Medicines used in respiratory diseases only seen in children

Authors :
A. L. Boner
Warren Lenney
Andrew Bush
J. Kimpen
M. Goetz
Anne Greenough
L. Bont
Ernst Eber
K-H. Carlsen
Brigitte Fauroux
J. Hull
M. Sanchez Luna
F.M. De Benedictis
Jonathan Grigg
Source :
The European respiratory journal. 34(3)
Publication Year :
2009

Abstract

Detailed literature searches were carried out in seven respiratory disease areas. Therapeutic evidence for efficacy of medicinal products was assessed using the Grades of Recommendation, Assessment and Evaluation (GRADE) methodology, as well as an assessment of safety and side-effects. Systemic corticosteroids may reduce the development of bronchopulmonary dysplasia but have serious side-effects. Antioxidants need further study to demonstrate whether they have long-term benefits. Treatments for acute bronchiolitis have shown little benefit but new antiviral and monoclonal antibodies need further assessment. Well-constructed studies are needed to confirm the value of inhaled corticosteroids and/or montelukast in the management of viral-induced wheeze. Corticosteroids are the treatment of choice in croup. Minimal or no information is available for the treatment of congenital lung abnormalities, bronchiolitis obliterans and interstitial lung disease.

Details

Language :
English
ISSN :
13993003 and 09031936
Volume :
34
Issue :
3
Database :
OpenAIRE
Journal :
The European respiratory journal
Accession number :
edsair.doi.dedup.....f958ef7a1d123c02096df4d77bfec844