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The Dose Response of Chromosome Aberrations in Human Lymphocytes InducedIn Vitroby Very Low-Dose γ Rays

Authors :
Mitsuaki A. Yoshida
Toshikazu Suzuki
Toshiyasu Iwasaki
Isamu Hayata
Yoshio Takashima
Source :
Radiation Research. 175:208-213
Publication Year :
2011
Publisher :
Radiation Research Society, 2011.

Abstract

This paper considers the dose–effect relationship for unstable chromosome aberration yields in human lymphocytes in very low-dose range. Data are presented for 60Co γ-ray doses of 0, 10, 20, 40 and 1000 mGy. More than 5,000 metaphases were scored for each data point at the very low doses, and each cell was double-checked using a semi-automated metaphase finding/relocation system. Aberration yields of dicentrics plus centric rings followed an excellent linear dose response down to zero dose; the yields were significantly above the control frequency from 20 mGy.

Details

ISSN :
19385404 and 00337587
Volume :
175
Database :
OpenAIRE
Journal :
Radiation Research
Accession number :
edsair.doi.dedup.....f979ac5dabf8c600e9c2114d2deaf6fd
Full Text :
https://doi.org/10.1667/rr2097.1