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An old friend: Uric acid and its association with fractional flow reserve
- Source :
- Turkish Journal of Medical Sciences, Volume: 49, Issue: 6 1614-1619
- Publication Year :
- 2019
- Publisher :
- The Scientific and Technological Research Council of Turkey (TUBITAK-ULAKBIM) - DIGITAL COMMONS JOURNALS, 2019.
-
Abstract
- Background/aim The aim of this study was to investigate the importance of preprocedural uric acid (UA) level in predicting fractional flow reserve (FFR) results of intermediate coronary lesions in patients with stable coronary artery disease undergoing coronary angiography. Materials and methods We retrospectively analyzed 293 patients who underwent FFR measurement to determine the significance of intermediate coronary stenosis detected by conventional coronary angiography. Patients were divided into 2 groups: Group 1 (n = 127) included patients with FFR of 0.80 (hemodynamically nonsignificant lesions). Uric acid levels were assessed in both groups with the enzymatic colorimetric method by clinical chemistry autoanalyzer. Results The mean UA level was significantly higher in patients whose FFR indicated hemodynamically significant coronary lesions (UA: 5.43 ± 1.29 mg/dL in Group 1 vs. 4.51 ± 1.34 mg/dL in Group 2, P < 0.001). Conclusion Elevated UA levels are associated with hemodynamically significant coronary lesions measured with FFR. Uric acid may be used as a predictor of hemodynamically compromised coronary lesions before FFR procedures.
- Subjects :
- Male
Coronary angiography
medicine.medical_specialty
Coronary stenosis
Fractional flow reserve
030204 cardiovascular system & hematology
Coronary Angiography
AutoAnalyzer
Article
intermediate coronary stenosis
Coronary artery disease
03 medical and health sciences
chemistry.chemical_compound
0302 clinical medicine
Internal medicine
medicine
Humans
In patient
fractional flow reserve
Retrospective Studies
0303 health sciences
030306 microbiology
business.industry
Coronary Stenosis
General Medicine
Middle Aged
Uric acid,fractional flow reserve,intermediate coronary stenosis
medicine.disease
Uric Acid
Fractional Flow Reserve, Myocardial
ROC Curve
chemistry
Cardiology
Uric acid
Female
business
Subjects
Details
- ISSN :
- 13036165 and 13000144
- Database :
- OpenAIRE
- Journal :
- TURKISH JOURNAL OF MEDICAL SCIENCES
- Accession number :
- edsair.doi.dedup.....f9cfdd050fbb0b9b01034b6d93870931