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Cortisol Production Rate. VII. Hypothyroidism and Hyperthyroidism in Infants and Children
- Source :
- The Journal of Clinical Endocrinology & Metabolism. 27:1616-1622
- Publication Year :
- 1967
- Publisher :
- The Endocrine Society, 1967.
-
Abstract
- Utilizing an in vivo isotope dilution technique based on 48 hr urine pools, cortisol production rates (CPRs) and urinary 17-hydroxycorticosteroids (17-OHCS) were estimated in 16 infants and children with hypothyroidism, and in 9 children and young adults with hyperthyroidism. The results were compared statistically with those obtained in 20 normal infants, children and young adults previously reported. Hypothyroid patients between the ages of 5 and 17 yr had a decrease in both CPR and 17-OHCS. However, 3 athyreotic cretins, less than 3 months old, and a mildly hypothyroid older infant had normal CPRs. In the hypothyroid patients there appeared to be a correlation between the duration and degree of hypothyroidism and the degree of depression of the CPR. Hyperthyroidism in the age group 5–17 yr induced a marked increase in CPR in only a few patients, while increasing the urinary 17-OHCS to a greater extent and with greater regularity.
- Subjects :
- Male
endocrine system
medicine.medical_specialty
Dilution technique
Adolescent
Hydrocortisone
endocrine system diseases
Endocrinology, Diabetes and Metabolism
medicine.medical_treatment
Urinary system
Clinical Biochemistry
Urine
Thyroid Function Tests
Hyperthyroidism
Biochemistry
Iodine Radioisotopes
Endocrinology
Adrenocorticotropic Hormone
Hypothyroidism
Internal medicine
medicine
Humans
Cardiopulmonary resuscitation
Young adult
Child
Depression (differential diagnoses)
17-Hydroxycorticosteroids
business.industry
Biochemistry (medical)
Infant
Child, Preschool
Female
business
hormones, hormone substitutes, and hormone antagonists
Production rate
medicine.drug
Subjects
Details
- ISSN :
- 19457197 and 0021972X
- Volume :
- 27
- Database :
- OpenAIRE
- Journal :
- The Journal of Clinical Endocrinology & Metabolism
- Accession number :
- edsair.doi.dedup.....fa1e88a1d3ddaeb69415a55b0b6c85e7
- Full Text :
- https://doi.org/10.1210/jcem-27-11-1616