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Effect of the Methanolic Extract of Glinus lotoides on Dalton's Ascitic Lymphoma

Authors :
K. T. Manisenthilkumar
G. Krishnamoorthy
S. Kavimani
R. Ilango
Source :
Biological and Pharmaceutical Bulletin. 22:1251-1252
Publication Year :
1999
Publisher :
Pharmaceutical Society of Japan, 1999.

Abstract

The antitumour activity of the methanolic extract of Glinus lotoides (MGL) has been evaluated against Dalton's ascitic lymphoma (DAL) in Swiss albino mice. A significant enhancement of mean survival time of tumour bearing mice and peritoneal cell count in normal mice was observed with respect to the control group. When these MGL treated animals underwent i.p. inoculation with DAL cells, tumour cell growth was found to be inhibited. After 14 d of inoculation, MGL is able to reverse the changes in the haemotological parameters, protein and packed cellular volume consequent to tumour inoculation.

Details

ISSN :
13475215 and 09186158
Volume :
22
Database :
OpenAIRE
Journal :
Biological and Pharmaceutical Bulletin
Accession number :
edsair.doi.dedup.....fa2f4f9a3eab76e9cf0b656bd306caae
Full Text :
https://doi.org/10.1248/bpb.22.1251