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Institutionally validated nomogram predicting prognosis for older patients with nonmetastatic nasopharyngeal carcinoma
- Source :
- Future Oncology. 18:1829-1838
- Publication Year :
- 2022
- Publisher :
- Future Medicine Ltd, 2022.
-
Abstract
- Aim: Older adult patients with nonmetastatic nasopharyngeal carcinoma (NPC) have poor outcomes relative to younger patients. The authors’ group established a nomogram to predict the overall survival of older adults with NPC and inform patient management. Methods: Cases with NPC (n = 782) were enrolled in this study; clinical data in the Surveillance, Epidemiology, and End Results database from 2010 to 2015 served as the training cohort (n = 657), and patients from Jiangxi Cancer Hospital (n = 125) served as the external validation cohort. Results: Training and external validation cohort C-index, receiver operator characteristics curves and calibration curves showed that our nomogram has great predictive ability. Conclusions: Compared with tumor-node-metastasis staging, this nomogram can help clinicians better predict the prognosis of older adults with nonmetastatic NPC.
Details
- ISSN :
- 17448301 and 14796694
- Volume :
- 18
- Database :
- OpenAIRE
- Journal :
- Future Oncology
- Accession number :
- edsair.doi.dedup.....fa6b1a38f125c10f378d38ef9172acd8