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Benefits and harm of systemic steroids for short- and long-term use in rhinitis and rhinosinusitis: an EAACI position paper

Authors :
Evelijn Lourijsen
Mika J. Mäkelä
Ludger Klimek
Ralph Mösges
Wytske Fokkens
Sanna Toppila-Salmi
Valérie Hox
Kristian Aasbjerg
Thibaut Van Zele
Philippe Gevaert
Claus Bachert
Joaquim Mullol
Koen Boussery
Arnout Jordens
Sophie Scheire
Paloma Campo
P. V. Tomazic
Laura Pujols
Martin Wagemann
Ioana Agache
Isam Alobid
Job F M van Boven
Michael Rudenko
Carmen Rondon
Claire Hopkins
Glenis Scadding
Peter Hellings
UCL - SSS/IREC/PNEU - Pôle de Pneumologie, ORL et Dermatologie
UCL - (SLuc) Service d'oto-rhino-laryngologie
Source :
Clinical and Translational Allergy, Vol 10, Iss 1, Pp 1-27 (2020), Clinical and translational allergy, Vol. 10, no.1, p. 1 (2020), Clinical and Translational Allergy, CLINICAL AND TRANSLATIONAL ALLERGY, Clinical Translational Allergy, Vol. 10, no.1, p. 1 (2020), Recercat. Dipósit de la Recerca de Catalunya, instname, Dipòsit Digital de la UB, Universidad de Barcelona
Publication Year :
2019

Abstract

Because of the inflammatory mechanisms of most chronic upper airway diseases such as rhinitis and chronic rhinosinusitis, systemic steroids have been used for their treatment for decades. However, it has been very well documented that-potentially severe-side-effects can occur with the accumulation of systemic steroid courses over the years. A consensus document summarizing the benefits of systemic steroids for each upper airway disease type, as well as highlighting the potential harms of this treatment is currently lacking. Therefore, a panel of international experts in the field of Rhinology reviewed the available literature with the aim of providing recommendations for the use of systemic steroids in treating upper airway disease. ispartof: CLINICAL AND TRANSLATIONAL ALLERGY vol:10 issue:1 ispartof: location:England status: published

Subjects

Subjects :
Rhinology
medical literature
evidence based medicine
Rhinosinusitis
adverse event
gastrointestinal symptom
otorhinolaryngology
eye disease
nose polyp
Systemic therapy
mental disease
systemic therapy
DOUBLE-BLIND
0302 clinical medicine
cardiovascular disease
ORAL STEROIDS
lipid metabolism
Medicine and Health Sciences
SEVERE NASAL POLYPOSIS
Cushingoid syndrome
Immunology and Allergy
030223 otorhinolaryngology
Rinitis
Rhinitis
acute rhinosinusitis
alternative medicine
drug effect
CORTICOSTEROID-THERAPY
immunosuppressive treatment
nose disease
Glucocorticosteroids
risk benefit analysis
3. Good health
ALLERGIC RHINITIS
priority journal
protein metabolism
SEASONAL
diabetes mellitus
drug induced disease
endocrine disease
BONE-MINERAL DENSITY
ENDOSCOPIC SINUS SURGERY
pediatric patient
Pulmonary and Respiratory Medicine
medicine.medical_specialty
hypothalamus hypophysis adrenal system
injection site discomfort
Immunology
drug cost
desensitization
review
autoimmune disease
fungal sinusitis
03 medical and health sciences
WEGENERS-GRANULOMATOSIS
drug activity
short course therapy
medicine
drug mechanism
carbohydrate metabolism
human
Intensive care medicine
Glucocorticoides
Glucocorticoids
avascular necrosis
peptic ulcer
Asthma
drug use
long term care
allergic rhinitis
calcium balance
business.industry
hypophysis disease
chronic rhinosinusitis
antiinflammatory activity
Evidence-based medicine
RC581-607
asthma
medicine.disease
osteoporosis
infection
Review article
RHEUMATOID-ARTHRITIS
drug efficacy
Upper respiratory tract infection
030228 respiratory system
hypothalamus disease
upper respiratory tract infection
occupational disease
glucocorticoid
GLUCOCORTICOID-RECEPTOR-ALPHA
hyperglycemia
Immunologic diseases. Allergy
Airway
business
Medical literature

Details

ISSN :
20457022
Volume :
10
Database :
OpenAIRE
Journal :
Clinical and translational allergy
Accession number :
edsair.doi.dedup.....faf600bc4193d2045db6743484507c52