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The Arabidopsis H3K27me3 demethylase JUMONJI 13 is a temperature and photoperiod dependent flowering repressor
- Source :
- Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019), Nature Communications
- Publication Year :
- 2019
- Publisher :
- Springer Science and Business Media LLC, 2019.
-
Abstract
- In plants, flowering time is controlled by environmental signals such as day-length and temperature, which regulate the floral pathway integrators, including FLOWERING LOCUS T (FT), by genetic and epigenetic mechanisms. Here, we identify an H3K27me3 demethylase, JUMONJI 13 (JMJ13), which regulates flowering time in Arabidopsis. Structural characterization of the JMJ13 catalytic domain in complex with its substrate peptide reveals that H3K27me3 is specifically recognized through hydrogen bonding and hydrophobic interactions. Under short-day conditions, the jmj13 mutant flowers early and has increased FT expression at high temperatures, but not at low temperatures. In contrast, jmj13 flowers early in long-day conditions regardless of temperature. Long-day condition and higher temperature induce the expression of JMJ13 and increase accumulation of JMJ13. Together, our data suggest that the H3K27me3 demethylase JMJ13 acts as a temperature- and photoperiod-dependent flowering repressor.<br />Jumonji domain-containing histone demethylases regulate flowering in plants. Here Zheng et al. show that Arabidopsis JMJ13 is an H3K27me3 demethylase that recognizes H3K27me3 via hydrogen bonding and hydrophobic interactions and affects both photoperiod and temperature-dependent flowering responses.
- Subjects :
- Models, Molecular
Protein Conformation, alpha-Helical
0301 basic medicine
Jumonji Domain-Containing Histone Demethylases
Light
Mutant
Arabidopsis
Gene Expression
General Physics and Astronomy
02 engineering and technology
Crystallography, X-Ray
Substrate Specificity
Histones
Protein structure
Gene Expression Regulation, Plant
Gene expression
Cloning, Molecular
lcsh:Science
Regulation of gene expression
photoperiodism
Multidisciplinary
biology
Chemistry
Temperature
Gene Expression Regulation, Developmental
food and beverages
021001 nanoscience & nanotechnology
Recombinant Proteins
Cell biology
0210 nano-technology
Hydrophobic and Hydrophilic Interactions
Protein Binding
Science
Photoperiod
Repressor
Flowers
macromolecular substances
Article
General Biochemistry, Genetics and Molecular Biology
03 medical and health sciences
Tobacco
Protein Interaction Domains and Motifs
Amino Acid Sequence
Binding Sites
Arabidopsis Proteins
fungi
Hydrogen Bonding
General Chemistry
biology.organism_classification
030104 developmental biology
Agrobacterium tumefaciens
Mutation
biology.protein
Demethylase
Protein Conformation, beta-Strand
lcsh:Q
Peptides
Subjects
Details
- ISSN :
- 20411723
- Volume :
- 10
- Database :
- OpenAIRE
- Journal :
- Nature Communications
- Accession number :
- edsair.doi.dedup.....fafe71ebbf43e23681f9811c20dfe413