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Current View on the Mechanisms of Alcohol-Mediated Toxicity
- Source :
- International Journal of Molecular Sciences, Vol 22, Iss 9686, p 9686 (2021), International Journal of Molecular Sciences
- Publication Year :
- 2021
- Publisher :
- MDPI AG, 2021.
-
Abstract
- Alcohol is a psychoactive substance that is widely used and, unfortunately, often abused. In addition to acute effects such as intoxication, it may cause many chronic pathological conditions. Some of the effects are very well described and explained, but there are still gaps in the explanation of empirically co-founded dysfunction in many alcohol-related conditions. This work focuses on reviewing actual knowledge about the toxic effects of ethanol and its degradation products.
- Subjects :
- Acute effects
medicine.medical_specialty
Alcohol Drinking
QH301-705.5
Psychoactive substance
Alcohol
Review
Catalysis
Gene Expression Regulation, Enzymologic
Inorganic Chemistry
chemistry.chemical_compound
Medicine
Humans
oxidative stress
Physical and Theoretical Chemistry
Biology (General)
Intensive care medicine
Molecular Biology
QD1-999
Spectroscopy
metabolization
business.industry
Organic Chemistry
Alcohol Dehydrogenase
toxicity
General Medicine
Computer Science Applications
Chemistry
chemistry
Organ Specificity
Toxicity
ethanol
business
Alcohol-Related Disorders
Metabolic Networks and Pathways
acetaldehyde
Subjects
Details
- Language :
- English
- ISSN :
- 16616596 and 14220067
- Volume :
- 22
- Issue :
- 9686
- Database :
- OpenAIRE
- Journal :
- International Journal of Molecular Sciences
- Accession number :
- edsair.doi.dedup.....fb7e9a78461afb1efe3c13d277ac34a0