Back to Search
Start Over
The current surgical treatment of pancreatic cancer in China: a national wide cross-sectional study
- Source :
- Journal of Pancreatology, Vol 2, Iss 1, Pp 16-21 (2019)
- Publication Year :
- 2019
- Publisher :
- Wolters Kluwer Health/LWW, 2019.
-
Abstract
- Objective: The aim of this study is to investigate the current status of pancreatic cancer patients undoing surgical treatment in China and to find ways to improve the survival of these patients in the future. Methods: This study is a national, multicenter, cross-sectional study in China. Information regarding pancreatic cancer patients undergoing surgical treatment from 34 high-volume tertiary IIIA level hospitals was collected and analyzed from the March 1, 2016 to the February 28, 2017. Results: In total, 2200 pancreatic cancer patients were enrolled from 34 tertiary IIIA level hospitals in 16 provinces across China. The male-to-female ratio was 1.5. More than 80% of the patients were between 50 and 70 years old. The top 4 symptoms were epigastric discomfort, abdominal pain, jaundice, and weight loss. Carbohydrate antigen 19-9 and carcinoembryonic antigen were elevated in 70.9% and 27.1 % of patients, respectively. A multidisciplinary team (MDT) discussion was carried out for 35.0% of patients before surgery. The proportion of minimally invasive pancreatic surgeries was approximately 20%. A total of 83.4% of the operations achieved R0 resection, and the incidence of grade 3/4 postoperative complications was 7.7%. Only 13.4% of the patients received postoperative adjuvant chemotherapy. The percentage of pathological stage I tumors was only 24.5%. Conclusion: The majority of pancreatic cancer patients undergoing surgical resection in China are in an advanced stage. The MDT consultations for pancreatic cancer have not been widely carried out. R0 resection has been achieved in most cases, with relatively low incidence of serious complications, but minimally invasive pancreatic surgery should be further promoted. The application of postoperative chemotherapy remains low. This national, multicentre, cross-sectional study comprehensively presents the current status of pancreatic cancer patients undergoing surgical treatment and shows the road to improve survival of these patients in the future. Key words: China; Current status; Pancreatic cancer; Pancreatic surgery; Treatment
- Subjects :
- Abdominal pain
medicine.medical_specialty
Hepatology
biology
business.industry
Cross-sectional study
Endocrinology, Diabetes and Metabolism
Incidence (epidemiology)
Cancer
RC799-869
Jaundice
Diseases of the digestive system. Gastroenterology
medicine.disease
Surgery
Endocrinology
Carcinoembryonic antigen
Weight loss
Pancreatic cancer
biology.protein
Medicine
medicine.symptom
business
Subjects
Details
- Language :
- English
- ISSN :
- 25773577 and 20965664
- Volume :
- 2
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- Journal of Pancreatology
- Accession number :
- edsair.doi.dedup.....fb910f90f1d83a4017f6483f6efdff7f