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A Precise Sampling Strip with Microstructures
- Source :
- EMBC
- Publication Year :
- 2018
- Publisher :
- IEEE, 2018.
-
Abstract
- This paper presents a precise sampling microstructure formed as a paper strip. We have been developing dialysis system that can be implanted into a human body as an artificial kidney. For the safe use of our artificial kidney, the patients' urine needs to be constantly monitored to detect the abnormal value of ion concentration essential for human life. We are conceiving the monitoring system based on sampling by a paper strip. In this study, we fabricated the strip consisting of slanted and interlocked micropillars for the sampling, known as synthetic microfluidic paper. The paper-like substrate can be fabricated with a well-controlled geometry and subsequently enables precise sampling. Through the conducted experiments, it was shown that synthetic microfluidic paper had better mechanical properties, showed more precision in sampling than paper filter as well as corresponding liquid holding capability to the paper filter. Our proposed paper-based sampling system is expected to lead to the development of minimally invasive ion monitoring system with quantitative sampling strip.
- Subjects :
- Paper
0301 basic medicine
Materials science
Human life
Acoustics
Microfluidics
030232 urology & nephrology
Sampling (statistics)
STRIPS
Urinalysis
Kidney
Microstructure
law.invention
Sampling system
03 medical and health sciences
030104 developmental biology
0302 clinical medicine
Renal Dialysis
law
Paper filter
Humans
Artificial Organs
Filtration
Subjects
Details
- Database :
- OpenAIRE
- Journal :
- 2018 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)
- Accession number :
- edsair.doi.dedup.....fb958c7f9197c79c1fa996d941da0937