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Improving anticoagulation in sub‐Saharan Africa: What are the challenges and how can we overcome them?

Authors :
Munir Pirmohamed
Karen Cohen
Johannes P. Mouton
Catriona Waitt
Christine Sekaggya-Wiltshire
Marc Blockman
Jerome Roy Semakula
Source :
British Journal of Clinical Pharmacology
Publication Year :
2021
Publisher :
Wiley, 2021.

Abstract

Patients in sub‐Saharan Africa generally have poor anticoagulation control. We review the potential reasons for this poor control, as well as the potential solutions. Challenges include the affordability and centralisation of anticoagulation care, problems with access to medicines and international normalised ratio monitoring, the lack of locally validated standardized dosing protocols, and low levels of anticoagulation knowledge among healthcare workers and patients. Increasing numbers of patients will need anticoagulation in the future because of the increasing burden of noncommunicable disease in the region. We propose that locally developed “warfarin care bundles” which address multiple anticoagulation challenges in combination may be the most appropriate solution in this setting currently.

Details

ISSN :
13652125 and 03065251
Volume :
87
Database :
OpenAIRE
Journal :
British Journal of Clinical Pharmacology
Accession number :
edsair.doi.dedup.....fbcf4cdf3de7b4236315bdc81cc7e33e