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Evaluation of a Capped Dosing Telavancin Regimen Compared to Standard Dosing at a Large Community Teaching Hospital

Authors :
Ali Hassoun
Fernando J Diggs
Spencer H Durham
Kimberly B. Garza
Jonathan Edwards
Source :
Antimicrob Agents Chemother
Publication Year :
2021

Abstract

Telavancin, a lipoglycopeptide antibiotic, is traditionally dosed at 10 mg/kg based on total body weight but is associated with toxicities that limit its use. This study supports the use of a capped dosing regimen of 750 mg in obese patients, which is associated with equal efficacy and fewer adverse effects compared to traditional dosing.

Details

ISSN :
10986596
Volume :
66
Issue :
1
Database :
OpenAIRE
Journal :
Antimicrobial agents and chemotherapy
Accession number :
edsair.doi.dedup.....fbe637bbb2cceb4e94da89ffd1e06e1b