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Evaluation of a Capped Dosing Telavancin Regimen Compared to Standard Dosing at a Large Community Teaching Hospital
- Source :
- Antimicrob Agents Chemother
- Publication Year :
- 2021
-
Abstract
- Telavancin, a lipoglycopeptide antibiotic, is traditionally dosed at 10 mg/kg based on total body weight but is associated with toxicities that limit its use. This study supports the use of a capped dosing regimen of 750 mg in obese patients, which is associated with equal efficacy and fewer adverse effects compared to traditional dosing.
- Subjects :
- medicine.medical_specialty
Lipoglycopeptide
medicine.drug_class
Antibiotics
Clinical Therapeutics
Teaching hospital
chemistry.chemical_compound
Telavancin
Internal medicine
medicine
Humans
Pharmacology (medical)
Dosing
Adverse effect
Hospitals, Teaching
Pharmacology
business.industry
Dosing regimen
Lipoglycopeptides
Anti-Bacterial Agents
Regimen
Infectious Diseases
Aminoglycosides
chemistry
business
medicine.drug
Subjects
Details
- ISSN :
- 10986596
- Volume :
- 66
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- Antimicrobial agents and chemotherapy
- Accession number :
- edsair.doi.dedup.....fbe637bbb2cceb4e94da89ffd1e06e1b